自由呼吸、屏气和呼吸触发扩散加权磁共振成像中肺癌表观扩散系数（ADC）测量的观察者间和观察者内一致性
Inter- and intraobserver agreement of ADC measurements of lung cancer in free breathing, breath-hold and respiratory triggered diffusion-weighted MRI.
作者信息
Cui Lei, Yin Jian-Bing, Hu Chun-Hong, Gong Shen-Chu, Xu Jun-Feng, Yang Ju-Shun
机构信息
Department of Radiology, First Affiliated Hospital of Soochow University, 188 Shixi Street, Suzhou, Jiangsu, PR China, 215006; Department of Radiology, Second Affiliated Hospital of Nantong University, 6 Hai'er Road, Chongchuan District, Nantong, Jiangsu, PR China, 226001.
Department of Radiology, Second Affiliated Hospital of Nantong University, 6 Hai'er Road, Chongchuan District, Nantong, Jiangsu, PR China, 226001.
出版信息
Clin Imaging. 2016 Sep-Oct;40(5):892-6. doi: 10.1016/j.clinimag.2016.04.002. Epub 2016 Apr 12.
OBJECTIVE
To prospectively evaluate the inter- and intraobserver agreement of apparent diffusion coefficient (ADC) measurements in free breathing, breath-hold, and respiratory triggered diffusion-weighted imaging (DWI) of lung cancer.
METHODS
Twenty-two patients with lung cancer (tumor size >2cm) underwent DWIs (3.0T) in three imaging methods. Lesion ADCs were measured twice by both of the two independent observers and compared.
RESULTS
No statistical significance was found among methods, though respiratory-triggered DWI tended to have higher ADCs than breath-hold DWI. Great inter- and intraobserver agreement was shown.
CONCLUSION
ADCs had good inter- and intraobserver agreement in all three DWI methods.
目的
前瞻性评估在自由呼吸、屏气和呼吸触发扩散加权成像（DWI）中，肺癌表观扩散系数（ADC）测量的观察者间和观察者内一致性。
方法
22例肺癌患者（肿瘤大小>2cm）接受了三种成像方法的DWI（3.0T）检查。两名独立观察者分别对病变的ADC值进行两次测量并比较。
结果
尽管呼吸触发DWI的ADC值往往高于屏气DWI，但三种方法之间未发现统计学差异。观察者间和观察者内一致性良好。
结论
在所有三种DWI方法中，ADC值的观察者间和观察者内一致性良好。
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