Albayrak Eda, Dogru Hatice Yılmaz, Ozmen Zafer, Altunkas Ayşegül, Kalayci Tugce Ozlem, Inci Mehmet Fatih, Server Sadık, Sonmezgoz Fitnet, Aktas Fatma, Demir Osman
Department of Radiology, Gaziosmanpasa University, Medical Faculty, Tokat, Turkey.
Department of Obstetrics and Gynecology, Gaziosmanpasa University, Medical Faculty, Tokat, Turkey.
Clin Imaging. 2016 Sep-Oct;40(5):926-30. doi: 10.1016/j.clinimag.2016.04.006. Epub 2016 Apr 26.
The aim of this study is to investigate the effectiveness of placental strain ratio (SR) values measured by real-time sonoelastography (SE) in the second trimester in the prediction of spontaneous preterm birth (sPTB).
This study included 70 pregnant women who applied to our clinic for routine second-trimester screening. Placental SR measurements were performed with the SE method. Two different SR measurements were performed by taking two different tissues as references. The SR value measured when taking the rectus abdominis muscle as a reference was termed the muscle-to-placenta strain ratio (MPSR), while the SR value measured when taking subcutaneous tissue as a reference was termed the fat-to-placenta strain ratio (FPSR). Women whose gestational age at birth was less than 37 weeks 0 days were accepted as sPTB. The association between gestational age at birth and MPSR and FPSR was investigated. Receiver operating characteristics analysis was used to calculate the sensitivity and specificity of the elastographic outcomes.
There was a low-level negative correlation between MPSR and gestational age at birth (r=-0.300, P=.012) and there was a moderate-level negative correlation between FPSR and gestational age at birth (r=-0.513, P<.001). The multivariate linear regression analysis showed that the FPSR (β=0.609, P=.002) was the significant predictor for the sPTB.
Our data indicate that the FPSR value measured with real-time SE in the second trimester of pregnancy may be effective in the prediction of sPTB.
本研究旨在探讨孕中期通过实时弹性成像（SE）测量的胎盘应变比（SR）值在预测自发性早产（sPTB）方面的有效性。
本研究纳入了70名到我院门诊进行常规孕中期筛查的孕妇。采用SE方法进行胎盘SR测量。以两种不同组织作为参照进行了两次不同的SR测量。以腹直肌为参照测量的SR值称为肌肉与胎盘应变比（MPSR），以皮下组织为参照测量的SR值称为脂肪与胎盘应变比（FPSR）。出生孕周小于37周0天的女性被视为sPTB。研究了出生孕周与MPSR和FPSR之间的关联。采用受试者操作特征分析来计算弹性成像结果的敏感性和特异性。
MPSR与出生孕周之间存在低度负相关（r = -0.300，P = 0.012），FPSR与出生孕周之间存在中度负相关（r = -0.513，P < 0.001）。多因素线性回归分析显示，FPSR（β = 0.609，P = 0.002）是sPTB的重要预测指标。
我们的数据表明，孕中期通过实时SE测量的FPSR值可能对sPTB具有预测作用。
