Bozkurt Hasan, Özer Samet, Yılmaz Resul, Sönmezgöz Ergün, Kazancı Özlem, Erbaş Oytun, Demir Osman
a Department of Child and Adolescent Psychiatry , Gaziosmanpasa University Hospital , Tokat , Turkey.
b Department of Pediatrics , Gaziosmanpasa University Hospital , Tokat , Turkey.
Appl Neuropsychol Child. 2017 Oct-Dec;6(4):262-268. doi: 10.1080/21622965.2016.1150184. Epub 2016 May 16.
Obesity is linked to adverse neurocognitive outcomes including reduced cognitive functioning. We aimed to investigate the differences in neuropsychological test performance of Turkish children and adolescents with obesity and healthy peers. Study includes 147 children and adolescents ranging in age from 8 to 16 years: 92 with obesity and 55 with healthy controls. After the participants were administered the Children's Depression Inventory (CDI) and the Screen for Child Anxiety Related Disorders (SCARED), they completed the battery tests of the Central Nervous System Vital Signs (CNSVS), a neurocognitive test battery, via computer. The battery calculates seven domain scores (Memory, Psychomotor speed, Processing speed, Reaction time, Complex attention, Executive Function, Cognitive flexibility), and a summary score (Neurocognition Index [NCI]). There was a statistically significant difference between the obesity and control groups on all cognitive domains. The mean NCI score of the obesity group was 81.3 ± 10.24 compared to 97.29 ± 4.97 for the control group. The mean NCI score in the obesity group was significantly lower than that of the control group (p < 0.001). The mean scores of other domains of obese patients were also found to be significantly lower than those of the control participants (p < 0.001). The mean SCARED scores of the participants with obesity were found to be significantly higher than those of the control participants (p < 0.05). However, no statistically significant relationship was found between the SCARED and the CNSVS scores. Cognitive dysfunction in children and adolescents with obesity should be taken into consideration when assessing and managing this population.
肥胖与不良神经认知结果相关，包括认知功能下降。我们旨在调查土耳其肥胖儿童和青少年与健康同龄人在神经心理测试表现上的差异。研究纳入了147名年龄在8至16岁之间的儿童和青少年：92名肥胖者和55名健康对照者。在参与者接受儿童抑郁量表（CDI）和儿童焦虑相关障碍筛查量表（SCARED）后，他们通过计算机完成了中枢神经系统生命体征（CNSVS）的成套测试，这是一种神经认知测试成套工具。该成套工具计算七个领域分数（记忆、心理运动速度、处理速度、反应时间、复杂注意力、执行功能、认知灵活性）和一个综合分数（神经认知指数[NCI]）。肥胖组和对照组在所有认知领域均存在统计学显著差异。肥胖组的平均NCI分数为81.3±10.24，而对照组为97.29±4.97。肥胖组的平均NCI分数显著低于对照组（p<0.001）。肥胖患者其他领域的平均分数也显著低于对照参与者（p<0.001）。肥胖参与者的平均SCARED分数显著高于对照参与者（p<0.05）。然而，未发现SCARED与CNSVS分数之间存在统计学显著关系。在评估和管理这一人群时，应考虑肥胖儿童和青少年的认知功能障碍。
