[类风湿关节炎中的纤维蛋白原 - 纤维蛋白 - 纤维蛋白溶解系统]
[The fibrinogen-fibrin-fibrinolysis system in rheumatoid arthritis].
作者信息
Belitskaia G A, Palienko I A, Shevchenko L I, Fedorova N E
出版信息
Vrach Delo. 1989 Jan(1):47-50.
PMID:2718445
Abstract
The enzymatic, nonenzymatic and XIIa-dependent fibrinolysis was inhibited. In RA without systemic manifestations the main cause of appearance of soluble complexes of monomeric fibrins (SCMF) in the blood is a local activation of coagulation in the inflamed joint tissues. It is suggested that an increase of SCMF concentration in the blood in patients with RA is a reliable and dynamic index of the activity of the inflammatory process.
摘要
酶促、非酶促和XIIa依赖的纤维蛋白溶解受到抑制。在无全身表现的类风湿关节炎中，血液中单体纤维蛋白可溶性复合物（SCMF）出现的主要原因是炎症关节组织中凝血的局部激活。有人提出，类风湿关节炎患者血液中SCMF浓度的升高是炎症过程活动的一个可靠且动态的指标。
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