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[遗传性鱼鳞病的皮纹特征]

[Dermatoglyphic characteristics in hereditary ichthyosis].

作者信息

Suvorova K N, Iudina I E

出版信息

Vestn Dermatol Venerol. 1989(1):18-20.

PMID:2718612
Abstract

Examination of 530 dermatoglyphic patterns of the palms and fingers in 265 patients with 5 nosologic forms of hereditary ichthyoses (autosomal dominant ichthyosis vulgaris, X-linked, congenital, lamellar, epidermolytic ichthyoses) have revealed significant differences in the pattern intensities and in the incidence rate of certain types of these patterns, associated with this or that form of ichthyosis; abnormalities in the flexor wrinkles of the ridge skin have been observed in all the studied forms of the disease, except the X-linked condition. The studies have revealed an abnormal roughness of the papillae on the epidermal ridges in epidermolytic ichthyosis and an obliterated dermatoglyphic pattern in lamellar ichthyosis. The detected changes in the ridge skin and the dermatoglyphic phenotypes may be useful for the differential diagnosis of these conditions.

摘要

对265例患有5种类型遗传性鱼鳞病(常染色体显性寻常型鱼鳞病、X连锁鱼鳞病、先天性鱼鳞病、板层状鱼鳞病、表皮松解性角化过度鱼鳞病)的患者的530个手掌和手指皮肤纹理图案进行检查后发现,这些图案的某些类型的图案强度和发生率存在显著差异,且与某种鱼鳞病形式相关;除X连锁型鱼鳞病外,在所有研究的疾病形式中均观察到嵴皮屈侧皱纹异常。研究发现,表皮松解性角化过度鱼鳞病患者表皮嵴上的乳头有异常粗糙,板层状鱼鳞病患者有皮肤纹理图案消失。在嵴皮和皮肤纹理表型中检测到的变化可能有助于这些疾病的鉴别诊断。

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