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单源计算机断层扫描对头颈部的双能计算机断层扫描血管造影:一种用于去除骨骼的新技术(分离滤波器)方法。

Dual-Energy Computed Tomography Angiography of the Head and Neck With Single-Source Computed Tomography: A New Technical (Split Filter) Approach for Bone Removal.

作者信息

Kaemmerer Nadine, Brand Michael, Hammon Matthias, May Matthias, Wuest Wolfgang, Krauss Bernhard, Uder Michael, Lell Michael M

机构信息

From the *Department of Radiology, University Hospital Erlangen-Nuremberg, Erlangen; and †Siemens AG, Healthcare Sector, Forchheim, Germany.

出版信息

Invest Radiol. 2016 Oct;51(10):618-23. doi: 10.1097/RLI.0000000000000290.

Abstract

OBJECTIVES

Dual-energy computed tomographic angiography (DE-CTA) has been demonstrated to improve the visualization of the head and neck vessels. The aim of this study was to test the potential of split-filter single-source dual-energy CT to automatically remove bone from the final CTA data set.

MATERIALS AND METHODS

Dual-energy CTA was performed in 50 consecutive patients to evaluate the supra-aortic arteries, either to grade carotid artery stenosis or to rule out traumatic dissections. Dual-energy CTA was performed on a 128-slice single-source CT system equipped with a special filter array to separate the 120-kV spectrum into a high- and a low-energy spectrum for DE-based automated bone removal. Image quality of fully automated bone suppression and subsequent manual optimization was evaluated by 2 radiologists on maximum intensity projections using a 4-grade scoring system. The effect of image reconstruction with an iterative metal artifact reduction algorithm on DE postprocessing was tested using a 3-grade scoring system, and the time demand for each postprocessing step was measured.

RESULTS

Two patients were excluded due to insufficient arterial contrast enhancement; in the remaining 48 patients, automated bone removal could be performed successfully. The addition of iterative metal artifact reduction algorithm improved image quality in 58.3% of the cases. After manual optimization, DE-CTA image quality was rated excellent in 7, good in 29, and moderate in 10 patients. Interobserver agreement was high (κ = 0.85). Stenosis grading was not influenced using DE-CTA with bone removal as compared with the original CTA. The time demand for DE image reconstruction was significantly higher than for single-energy reconstruction (42.1 vs 20.9 seconds).

CONCLUSIONS

Our results suggest that bone removal in DE-CTA of the head and neck vessels with a single-source CT is feasible and can be performed within acceptable time and moderate user interaction.

摘要

目的

双能计算机断层血管造影(DE-CTA)已被证明可改善头颈部血管的可视化。本研究的目的是测试分体式滤过器单源双能CT自动从最终CTA数据集中去除骨骼的潜力。

材料与方法

对50例连续患者进行双能CTA以评估主动脉弓上动脉,目的是对颈动脉狭窄进行分级或排除创伤性夹层。双能CTA在配备特殊滤过器阵列的128层单源CT系统上进行,该滤过器阵列将120 kV光谱分离为高能和低能光谱,用于基于双能的自动去骨。由2名放射科医生使用4级评分系统在最大强度投影上评估完全自动化去骨及随后手动优化后的图像质量。使用3级评分系统测试采用迭代金属伪影减少算法进行图像重建对双能后处理的影响,并测量每个后处理步骤的时间需求。

结果

2例患者因动脉对比增强不足被排除;其余48例患者成功进行了自动去骨。在58.3%的病例中,添加迭代金属伪影减少算法改善了图像质量。手动优化后,7例患者的DE-CTA图像质量评为优秀,29例为良好,10例为中等。观察者间一致性较高(κ = 0.85)。与原始CTA相比,使用去骨的DE-CTA不影响狭窄分级。双能图像重建的时间需求明显高于单能重建(42.1秒对20.9秒)。

结论

我们的结果表明,使用单源CT对头颈部血管进行DE-CTA去骨是可行的,并且可以在可接受的时间内并通过适度的用户交互来完成。

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