Dewey Kathryn G
Department of Nutrition and Program in International and Community Nutrition, University of California, Davis, Davis, California, USA.
Matern Child Nutr. 2016 May;12 Suppl 1(Suppl 1):27-38. doi: 10.1111/mcn.12282.
Meeting the high nutrient needs of pregnant and lactating women and their young children in regions such as South Asia is challenging because diets are dominated by staple foods with low nutrient density and poor mineral bioavailability. Gaps in nutritional adequacy in such populations probably date back to the agricultural revolution ~10 000 years ago. Options for improving diets during the first 1000 days include dietary diversification and increased intake of nutrient-rich foods, improved complementary feeding practices, micronutrient supplements and fortified foods or products specifically designed for these target groups. Evidence from intervention trials indicates that several of these strategies, both prenatal and post-natal, can have a positive impact on child growth, but results are mixed and a growth response is not always observed. Nutrition interventions, by themselves, may not result in the desired impact if the target population suffers from frequent infection, both clinical and subclinical. Further research is needed to understand the mechanisms underlying both prenatal and post-natal growth restriction. In the meantime, implementation and rigorous evaluation of integrated interventions that address the multiple causes of stunting is a high priority. These intervention packages should ideally include improved nutrition during both pregnancy and the post-natal period, prevention and control of prenatal and post-natal infection and subclinical conditions that restrict growth, care for women and children and stimulation of early child development. In regions such as South Asia, such strategies hold great promise for reducing stunting and enhancing human capital formation.
在南亚等地区,满足孕妇、哺乳期妇女及其幼儿对高营养的需求具有挑战性,因为这些地区的饮食以营养密度低且矿物质生物利用率差的主食为主。这类人群营养充足方面的差距可能要追溯到约一万年前的农业革命。在生命最初1000天内改善饮食的方法包括饮食多样化、增加营养丰富食物的摄入量、改进辅食喂养方法、补充微量营养素以及食用专门为这些目标群体设计的强化食品或产品。干预试验的证据表明,这些策略中的几种,无论产前还是产后,都可能对儿童生长产生积极影响,但结果不一,并非总能观察到生长反应。如果目标人群频繁遭受临床和亚临床感染,营养干预本身可能不会产生预期效果。需要进一步研究以了解产前和产后生长受限的潜在机制。与此同时,实施并严格评估针对发育迟缓多种成因的综合干预措施是当务之急。这些干预方案理想情况下应包括孕期和产后营养改善、预防和控制限制生长的产前和产后感染及亚临床状况、关爱妇女和儿童以及促进幼儿早期发育。在南亚等地区,这类策略对于减少发育迟缓及加强人力资本形成大有希望。