Li W, Wang D Z, Shen C F, Zhang Y, Jiang G H
Tianjin Center for Disease Control and Prevention, Tianjin 300011, China.
Zhonghua Liu Xing Bing Xue Za Zhi. 2016 May;37(5):699-701. doi: 10.3760/cma.j.issn.0254-6450.2016.05.023.
To investigate the change of incidence and age distribution of cervical cancer in Tianjin from 2007 to 2013.
The incidence data of cervical cancer and population data were collected from the cancer registry system of Tianjin Center for Disease Control and Prevention and Tianjin Municipal Public Security Bureau, respectively. The crude incidence, and age-standardized incidence of cervical cancer were calculated by using SPSS software. The Join Point Regression Program software was used to detect the trend of cervical cancer incidence.
A total of 3 362 cervical cancer patients were diagnosed during 2007 to 2013. The average age of the patients was 48.11 years. The crude incidence was 9.85/100 000. The annual world standard age specific incidence was 6.65 /100 000. The incidence in urban area was higher than that in rural area, but the proportion of the cases in urban area showed a downward trend(trend χ(2)=21.92, P=0.001)and the proportion of the cases in rural area showed a upward trend(trend χ(2)=12.70, P=0.048). The difference was significant. The incidence was generally stable in urban area, the APC value was 2.7%(95%CI:-9.1%-16.2%), the difference was not significant(Z=0.564, P=0.597); The incidence rate in rural area showed an upward trend, APC value was 13.4%(95% CI: 3.5%-24.2%), the difference was significant(Z=3.549, P=0.016). The two incidence peaks were in age groups 40-44 years and 75-79 years.
The overall incidence of cervical cancer in Tianjin was still stable during 2007-2013, and the disease mainly occurred in middle-aged and elderly population. More attention should be paid to the increased incidence of cervical cancer in rural area.
探讨2007年至2013年天津市宫颈癌发病率及年龄分布的变化。
分别从天津市疾病预防控制中心癌症登记系统和天津市公安局收集宫颈癌发病数据和人口数据。使用SPSS软件计算宫颈癌的粗发病率和年龄标准化发病率。采用Join Point回归程序软件检测宫颈癌发病率的趋势。
2007年至2013年共诊断出3362例宫颈癌患者。患者的平均年龄为48.11岁。粗发病率为9.85/10万。年度世界标准年龄别发病率为6.65/10万。城区发病率高于农村地区，但城区病例比例呈下降趋势（趋势χ²=21.92，P=0.001），农村地区病例比例呈上升趋势（趋势χ²=12.70，P=0.048）。差异有统计学意义。城区发病率总体稳定，APC值为2.7%（95%CI：-9.1%16.2%），差异无统计学意义（Z=0.564，P=0.597）；农村地区发病率呈上升趋势，APC值为13.4%（95%CI：3.5%24.2%），差异有统计学意义（Z=3.549，P=0.016）。两个发病高峰出现在4044岁和7579岁年龄组。
2007—2013年天津市宫颈癌总体发病率仍稳定，发病主要集中在中老年人群。农村地区宫颈癌发病率上升应引起更多关注。
