Huang Yuesheng
Institute of Burn Research, Southwest Hospital, State Key Laboratory of Trauma, Burns and Combined Injury, the Third Military Medical University, Chongqing 400038, China.
Zhonghua Shao Shang Za Zhi. 2016 May;32(5):257-9. doi: 10.3760/cma.j.issn.1009-2587.2016.05.001.
A series of studies demonstrated that myocardial damage and cardiac dysfunction occurs immediately following severe burn, even before significant reduction in blood volume due to increased capillary permeability. Such myocardial damage and cardiac dysfunction leads to cardiac deficiency, and it is a precipitating factor for burn shock and ischemic/hypoxic injury. In recent years, many experimental and clinical studies elucidated the pathogenesis and confirmed the clinical importance of prevention and treatment of"shock heart"in the early stage post severe burn.
一系列研究表明，严重烧伤后立即会发生心肌损伤和心脏功能障碍，甚至在因毛细血管通透性增加导致血容量显著减少之前就已出现。这种心肌损伤和心脏功能障碍会导致心功能不全，是烧伤休克和缺血/缺氧性损伤的一个促发因素。近年来，许多实验和临床研究阐明了其发病机制，并证实了严重烧伤后早期预防和治疗“休克心”的临床重要性。
