1型神经纤维瘤病学龄前儿童新兴执行功能的家长和教师观点：与未受影响儿童及基于实验室测量的比较
Parent and Teacher Perspectives on Emerging Executive Functioning in Preschoolers With Neurofibromatosis Type 1: Comparison to Unaffected Children and Lab-Based Measures.
作者信息
Casnar Christina L, Klein-Tasman Bonita P
机构信息
Department of Psychology, University of Wisconsin-Milwaukee, Milwaukee, WI, USA.
出版信息
J Pediatr Psychol. 2017 Mar 1;42(2):198-207. doi: 10.1093/jpepsy/jsw042.
OBJECTIVE
Children with neurofibromatosis type 1 (NF1) are at risk for executive functioning (EF) challenges, with little research with preschoolers.
METHODS
EF was examined using parent and teacher ratings of preschool-aged children with NF1 ( n = 26) and parent ratings of unaffected children ( n = 37) on the Behavior Rating Inventory for Executive Functioning-Preschool Form. Relations to performance on laboratory measures were also examined.
RESULTS
Based on parent ratings, children with NF1 had more dysfunction than the normative mean on the Working Memory (WM) scale and Emergent Metacognition Index (EMI). Teacher ratings indicated greater dysfunction than the normative mean on the WM and Planning/Organization scales, EMI, and General Executive Composite. Children with NF1 showed more difficulties than unaffected children on the WM scale. Teacher report of WM was significantly correlated with Differential Ability Scales-Second Edition Digits Forward performance.
CONCLUSIONS
WM emerged as an area of difficulty for young children with NF1.
目的
1型神经纤维瘤病（NF1）患儿存在执行功能（EF）方面的挑战风险，而针对学龄前儿童的研究较少。
方法
使用父母和教师对NF1学龄前儿童（n = 26）的评分以及对未受影响儿童（n = 37）父母在执行功能学龄前版行为评定量表上的评分来检查执行功能。还检查了与实验室测量表现的关系。
结果
根据父母评分，NF1患儿在工作记忆（WM）量表和新兴元认知指数（EMI）上的功能障碍比正常均值更多。教师评分表明，在WM和计划/组织量表、EMI以及总体执行综合量表上的功能障碍比正常均值更大。NF1患儿在WM量表上比未受影响的儿童表现出更多困难。教师对WM的报告与差异能力量表第二版顺背数字表现显著相关。
结论
工作记忆是NF1幼儿的一个困难领域。
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