Caselli M, Figura N, Trevisani L, Pazzi P, Guglielmetti P, Bovolenta M R, Stabellini G
First Department of Medicine, St. Anna Hospital of Ferrara, Italy.
Am J Gastroenterol. 1989 May;84(5):511-3.
Since the exact mechanisms of the pathogenicity of Campylobacter pylori are not known, we performed an ultrastructural study with the aim of focusing on patterns of possible physical contact between C. pylori and gastric epithelium, and of considering them in relation to the bacterial pathogenicity. Among 20 random consecutive patients referred for routine gastroscopy, we studied ultrathin sections from the 11 patients with Campylobacter-like organisms, and recognized three patterns of physical contact between bacteria and epithelial cells. These patterns seem in accord with published data of C. pylori toxicity, and they could represent different evolutive stages of the infection.
由于幽门螺杆菌致病的确切机制尚不清楚，我们进行了一项超微结构研究，旨在关注幽门螺杆菌与胃上皮细胞之间可能的物理接触模式，并结合细菌致病性对其进行研究。在随机连续转诊进行常规胃镜检查的20例患者中，我们研究了11例有类弯曲杆菌生物体患者的超薄切片，识别出细菌与上皮细胞之间的三种物理接触模式。这些模式似乎与已发表的幽门螺杆菌毒性数据一致，它们可能代表感染的不同演变阶段。
