Chauhan Vidyalaxmi, Shah Maitri C, Patel Sangita V, Marfatia Yogesh S, Zalavadiya Dhara
Department of Obstetrics and Gynecology, Government Medical College, Baroda, Gujarat, India.
Department of Community Medicine, Government Medical College, Baroda, Gujarat, India.
Indian J Sex Transm Dis AIDS. 2016 Jan-Jun;37(1):28-32. doi: 10.4103/0253-7184.176215.
In spite of a few shortcomings such as over diagnosis and over treatment, syndromic management is a recommended practice in India for sexually transmitted infections (STIs). This study tries to find out the efficacy of syndromic management measured as symptomatic improvement in females with vaginal discharge syndrome.
The objective of the study is to find out the effectiveness of syndromic management in terms of symptomatic improvement among females with vaginal discharge syndrome.
A longitudinal study was conducted in Gynecology Department of Tertiary Care Hospital including 180 symptomatic females having vaginal discharge syndrome. Demographic profile, presenting complaints, menstrual history, obstetric history, partner history, and contraceptive history were noted. This was followed by clinical examination and specimen collection for laboratory tests and blood tests to find out type of STI including viral STI such as human immunodeficiency virus (HIV), herpes simplex virus (HSV), and hepatitis B surface antigen (HBsAg). Treatment was given according to syndromic management on the same day. All the participants were asked to come for follow-up after 15 days and their improvement in symptoms was noted as complete improvement, some improvement or no improvement on a five point scale.
63.9% cases showed complete improvement, while 36.1% showed some improvement. None of the patients was without any improvement. Vaginal discharge syndrome was most common between 20 and 30 years (43.4%), and 67.8% of symptomatic females with vaginal discharge syndrome belonged to the lower socioeconomic group. HSV infection was the most common (15%) associated viral infection with vaginal discharge syndrome, while hepatitis B infection was the least common (0.5%). HIV was reactive in 2.8% cases only.
Syndromic management was found to be effective in relieving symptoms in most of the cases of vaginal discharge syndrome.
尽管存在过度诊断和过度治疗等一些缺点，但在印度，性传播感染（STIs）的综合征管理仍是一种推荐的做法。本研究试图找出以阴道分泌物综合征女性症状改善来衡量的综合征管理的疗效。
本研究的目的是找出综合征管理在阴道分泌物综合征女性症状改善方面的有效性。
在一家三级护理医院的妇科进行了一项纵向研究，纳入了180名有阴道分泌物综合征症状的女性。记录了人口统计学资料、主诉、月经史、产科史、性伴侣史和避孕史。随后进行临床检查并采集标本进行实验室检查和血液检查，以确定性传播感染的类型，包括病毒性性传播感染，如人类免疫缺陷病毒（HIV）、单纯疱疹病毒（HSV）和乙型肝炎表面抗原（HBsAg）。当天根据综合征管理进行治疗。所有参与者被要求在15天后前来随访，并将其症状改善情况按五分制记录为完全改善、部分改善或无改善。
63.9%的病例显示完全改善，而36.1%显示部分改善。没有患者无任何改善。阴道分泌物综合征在20至30岁之间最为常见（43.4%），67.8%有阴道分泌物综合征症状的女性属于社会经济地位较低的群体。HSV感染是与阴道分泌物综合征相关的最常见病毒感染（15%），而乙型肝炎感染最不常见（0.5%）。仅2.8%的病例HIV呈阳性反应。
发现综合征管理在大多数阴道分泌物综合征病例中能有效缓解症状。
