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伊马替尼治疗博来霉素诱导的肺毒性:一例病例报告及循证综述

Imatinib for bleomycin induced pulmonary toxicity: a case report and evidence-base review.

作者信息

Banakh Iouri, Lam Alice, Tiruvoipati Ravindranath, Carney Ian, Botha John

机构信息

Department of Pharmacy Frankston Hospital Peninsula Health Frankston Vic. Australia.

Department of Intensive Care Medicine Frankston Hospital Frankston Vic.3199 Australia; School of Public Health Faculty of Medicine, Nursing and Health Sciences Monash University Clayton Vic. 3800 Australia.

出版信息

Clin Case Rep. 2016 Apr 1;4(5):486-90. doi: 10.1002/ccr3.549. eCollection 2016 May.

Abstract

The evidence supporting therapy with imatinib for bleomycin-induced pneumonitis (BIP) is equivocal. Further experience is needed to establish its role in BIP management. While it may be considered in the management of BIP, it is important to be mindful of the adverse effects including thrombocytopenia and gastrointestinal bleeding.

摘要

支持伊马替尼治疗博来霉素诱导的肺炎(BIP)的证据并不明确。需要更多经验来确定其在BIP治疗中的作用。虽然在BIP治疗中可以考虑使用伊马替尼,但重要的是要注意其不良反应,包括血小板减少和胃肠道出血。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/20f5/4856242/e0a4d458e787/CCR3-4-486-g001.jpg

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