Kataria Nidhi, Singh Amarjit, Bedi Preet Kamal
Pathologist, Department of Pathology, Government Medical College , Amritsar, Punjab, India .
Professor, Department of Pathology, Government Medical College , Amritsar, Punjab, India .
J Clin Diagn Res. 2016 Apr;10(4):ED03-4. doi: 10.7860/JCDR/2016/17222.7540. Epub 2016 Apr 1.
Chorangioma is a nontrophoblastic benign vascular tumour of the placenta, arising from the primitive chorionic mesenchyme. The clinical significance is related to the size of the tumours. Small chorangiomas, with a frequency of about 1%, are often asymptomatic. On the contrary, giant chorangiomas, greater than 5 cm in diameter, are rare tumours, with prevalence ranging from 1:9,000 to 1:50,000, and often associated with a variety of pregnancy complications and a poor perinatal outcome. We report a case of 26-year-old female who presented to us at 36 weeks of gestation with pain in the lower abdomen. Ultrasonograpy revealed polyhydramnios and a vascular tumour on the surface of placenta. Proper conservative antenatal management was done and a full term healthy baby was delievered. Histopathological examination of the extracted mass confirmed the diagnosis of chorangioma. The novelty of this report lies in the presence of large nontrophoblastic vascular placental tumour and the absence of any fetal complications. We emphasise the need of regular and timely antenatal management to diagnose and treat the complications of chorangioma at an early stage.
绒毛膜血管瘤是一种胎盘的非滋养层良性血管肿瘤,起源于原始绒毛膜间充质。其临床意义与肿瘤大小有关。小的绒毛膜血管瘤发生率约为1%,通常无症状。相反,直径大于5cm的巨大绒毛膜血管瘤是罕见肿瘤,患病率在1:9000至1:50000之间,常伴有多种妊娠并发症及不良围产期结局。我们报告一例26岁女性,在妊娠36周时因下腹部疼痛前来就诊。超声检查显示羊水过多及胎盘表面有一血管肿瘤。进行了适当的保守产前管理,分娩出一个足月健康婴儿。对切除肿物的组织病理学检查确诊为绒毛膜血管瘤。本报告的新颖之处在于存在巨大的非滋养层胎盘血管肿瘤且无任何胎儿并发症。我们强调需要定期及时进行产前管理,以便早期诊断和治疗绒毛膜血管瘤的并发症。