Department of Medical, Surgical and Health Sciences, Neurologic Clinic, Headache Centre, University of Trieste, Cattinara Hospital, Trieste, Italy..
Department of Medical, Surgical and Health Sciences, Neurologic Clinic, Headache Centre, University of Trieste, Cattinara Hospital, Trieste, Italy.
Headache. 2016 Oct;56(9):1503-1506. doi: 10.1111/head.12844. Epub 2016 May 18.
Short-lasting unilateral neuralgiform headache attacks with conjunctival injection and tearing (SUNCT) and hypnic headache (HH) are two exceedingly rare and distinctly classified primary headaches. The hypothalamus seems to be a crucial region involved in the pathophysiology of both conditions, but no cases of SUNCT and HH co-occurrence have been described so far.
A 49-year-old woman who has been suffering from SUNCT for years, with alternation of symptomatic periods and remissions, developed a new headache with different clinical features, presenting exclusively during sleep and with a dramatic responsiveness to caffeine, that met the diagnostic criteria for HH.
The available literature suggests that SUNCT and HH are different conditions but the association in the same patient that we describe supports the concept that they are not mutually exclusive. Further studies are needed to establish if they share a common pathophysiological mechanism.
短暂单侧神经性头痛发作伴结膜充血和流泪（SUNCT）和催眠性头痛（HH）是两种极其罕见且明确分类的原发性头痛。下丘脑似乎是这两种病症病理生理学中的关键区域，但迄今为止尚未描述过 SUNCT 和 HH 同时发生的病例。
一位 49 岁的女性多年来一直患有 SUNCT，症状期和缓解期交替出现，出现了一种新的头痛，具有不同的临床特征，仅在睡眠时出现，并且对咖啡因反应强烈，符合 HH 的诊断标准。
现有文献表明，SUNCT 和 HH 是不同的病症，但我们描述的同一患者同时出现这两种病症支持这样一种观点，即它们并非互斥。需要进一步的研究来确定它们是否存在共同的病理生理机制。
