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烧伤皮肤的婴儿多发性大化脓性肉芽肿。病例报告及文献复习。

Infantile multiple large pyogenic granuloma on burned skin. Case report and review of literature.

作者信息

Dastgheib Ladan, Maghami Zohreh, Aslani Fatemeh Sari

机构信息

Shiraz University of Medical Sciences, Shiraz, Iran.

出版信息

An Bras Dermatol. 2016 Apr;91(2):212-4. doi: 10.1590/abd1806-4841.20164060.

DOI:10.1590/abd1806-4841.20164060
PMID:27192522
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC4861570/
Abstract

Pyogenic granuloma (PG) is a benign vascular lesion of the skin and mucous membranes, presenting as a solitary, red, pedunculated papule that bleeds easily and which appears to be a reactive vascular proliferation to minor injury. These lesions are more common in children and are mostly seen in exposed sites. Multiple disseminated PG is a rare condition. This report describes an infant with multiple, disseminated, pyogenic granulomas following burns from boiling milk. We reviewed literature published in English and found 9 cases. Six cases were provoked by hot milk, 2 by hot water, while the cause of the other case is unknown. Angiogiogenetic activity in milk may explain PG development in these patients.

摘要

化脓性肉芽肿(PG)是一种皮肤和黏膜的良性血管病变,表现为单个、红色、带蒂的丘疹,易出血,似乎是对轻微损伤的一种反应性血管增生。这些病变在儿童中更常见,大多见于暴露部位。多发性播散性PG是一种罕见情况。本报告描述了一名因沸牛奶烫伤后出现多发性播散性化脓性肉芽肿的婴儿。我们查阅了英文发表的文献,发现9例。6例由热牛奶诱发,2例由热水诱发,另一例病因不明。牛奶中的血管生成活性可能解释了这些患者中PG的发生。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/ba02/4861570/f74e21df302a/abd-91-02-0212-g04.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/ba02/4861570/217a6ac697cd/abd-91-02-0212-g01.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/ba02/4861570/014a8cffccca/abd-91-02-0212-g02.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/ba02/4861570/575794bbd8ab/abd-91-02-0212-g03.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/ba02/4861570/f74e21df302a/abd-91-02-0212-g04.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/ba02/4861570/217a6ac697cd/abd-91-02-0212-g01.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/ba02/4861570/014a8cffccca/abd-91-02-0212-g02.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/ba02/4861570/575794bbd8ab/abd-91-02-0212-g03.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/ba02/4861570/f74e21df302a/abd-91-02-0212-g04.jpg

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本文引用的文献

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Multiple disseminated pyogenic granuloma after second degree scald burn: a rare two case.二度烫伤后多发性播散性化脓性肉芽肿:罕见的两例病例
Int J Burns Trauma. 2013 Apr 18;3(2):125-9. Print 2013.
2
A case of multiple, eruptive pyogenic granuloma developed on a region of the burned skin: can erythromycin be a treatment option?一例烧伤皮肤区域出现的多发性、暴发性化脓性肉芽肿:红霉素能否作为一种治疗选择?
J Burn Care Res. 2007 Sep-Oct;28(5):754-7. doi: 10.1097/BCR.0B013E318148CB3F.
3
Multiple giant disseminated pyogenic granuloma in a burn lesion.
烧伤后脓性肉芽肿:一例报告并文献复习
Int J Burns Trauma. 2022 Jun 15;12(3):127-130. eCollection 2022.
4
Multiple disseminated pyogenic granuloma post-oil burning-Review literature.油烫伤后多发性播散性化脓性肉芽肿——文献综述
Clin Case Rep. 2020 Nov 6;9(1):169-172. doi: 10.1002/ccr3.3491. eCollection 2021 Jan.
烧伤病灶内多发巨大播散性化脓性肉芽肿
J Burn Care Res. 2006 Mar-Apr;27(2):247-9. doi: 10.1097/01.BCR.0000202642.08806.B7.
4
Pyogenic granuloma with multiple and satellite involvement after a burn in a 5-year-old child.一名5岁儿童烧伤后出现多发及卫星状分布的化脓性肉芽肿。
J Dermatol. 2006 Feb;33(2):150-2. doi: 10.1111/j.1346-8138.2006.00033.x.
5
[Milk angiogenin (Review)].[乳血管生成素(综述)]
Prikl Biokhim Mikrobiol. 2002 May-Jun;38(3):229-36.
6
[Angiogenin: involvement in angiogenesis and tumour growth].血管生成素:参与血管生成和肿瘤生长
Bull Cancer. 2001 Aug;88(8):725-32.
7
Pyogenic granuloma with multiple dissemination in a burn lesion.烧伤病灶中伴有多发播散的化脓性肉芽肿。
Pediatr Dermatol. 1997 May-Jun;14(3):213-5. doi: 10.1111/j.1525-1470.1997.tb00240.x.
8
Multiple giant disseminated pyogenic granuloma in three patients burned by boiling milk.三名被煮沸牛奶烫伤的患者出现多发性巨大播散性化脓性肉芽肿。
Int J Dermatol. 1995 Oct;34(10):707-10. doi: 10.1111/j.1365-4362.1995.tb04658.x.