巴西东南部一个非大都市血库四年期间人类嗜T淋巴细胞病毒流行率/合并感染率评估。
Evaluation of human T-lymphotropic virus prevalence/co-infection rates for a four-year period in a non-metropolitan blood center in Southeast Brazil.
作者信息
Pinto Mariana Tomazini, Slavov Svetoslav Nanev, Valente Vanderléia Bárbaro, Ubiali Eugênia Maria Amorim, Covas Dimas Tadeu, Kashima Simone
机构信息
Fundação Hemocentro de Ribeirão Preto, Faculdade de Medicina de Ribeirão Preto, Universidade de São Paulo, Ribeirão Preto, São Paulo, Brazil.
出版信息
Rev Soc Bras Med Trop. 2016 Apr;49(2):232-6. doi: 10.1590/0037-8682-0282-2015.
INTRODUCTION
Human T-lymphotropic virus types 1/2 (HTLV-1/2) are distributed worldwide and are endemic in specific regions.
METHODS
Serological evaluation of the HTLV-1/2 prevalence and co-infection rate [human immunodeficiency virus (HIV), hepatitis B virus (HBV), hepatitis C virus (HCV), Chagas disease, and syphilis)] for 2011-2014 was performed with volunteer blood donors from the western part of São Paulo State.
RESULTS
Serrana and Araçatuba had higher HTLV seroprevalence rates (0.1%); while Franca, Olimpia, and Bebedouro had lower seroprevalences (0.04%). Co-infection (HBV and syphilis) was present in 12.3% of HTLV-infected blood donors.
CONCLUSIONS
Our findings provide data for the prevalence of HTLV in Brazil and demonstrate the importance of regional and global hemovigilance.
引言
人类嗜T淋巴细胞病毒1型/2型（HTLV-1/2）在全球范围内均有分布，且在特定地区呈地方性流行。
方法
对2011年至2014年圣保罗州西部的志愿献血者进行了HTLV-1/2流行率及合并感染率[人类免疫缺陷病毒（HIV）、乙型肝炎病毒（HBV）、丙型肝炎病毒（HCV）、恰加斯病和梅毒]的血清学评估。
结果
塞拉纳和阿拉萨图巴的HTLV血清阳性率较高（0.1%）；而弗朗卡、奥林匹亚和贝贝杜罗的血清阳性率较低（0.04%）。12.3%的HTLV感染献血者存在合并感染（HBV和梅毒）。
结论
我们的研究结果提供了巴西HTLV流行情况的数据，并证明了区域和全球血液监测的重要性。
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