Shutka B V, Klipich Ia I, Mel'man E P
Biull Eksp Biol Med. 1989 Apr;107(4):498-500.
In experiments on 30 white mongrel adult rats of both sexes pathologic and reparative alterations in the kidney by the 30th day after recanalization of the ureter occluded for 1, 3, 7, 10, 15, 30 days have been studied using microdissection, light optic and electron microscopic methods. The fact has been established that in early times of HT (1 to 3 days) with the following reduction of urinary passage through the ureter (30 days), the canalicular-vascular formations of the kidney acquire normal morphological structure. In cases of more prolonged occlusion of the ureter (15 to 30 days) in the kidney noticeable destructive alterations prevail with replacement of parenchymatous elements by connective tissue.
在对30只成年白色杂种雌雄大鼠进行的实验中，采用显微解剖、光学显微镜和电子显微镜方法，研究了输尿管闭塞1、3、7、10、15、30天后至第30天肾脏的病理和修复性改变。已经证实，在输尿管梗阻早期（1至3天），随后输尿管尿流减少（30天）时，肾脏的小管-血管结构获得正常形态结构。在输尿管梗阻时间更长（15至30天）的情况下，肾脏中明显的破坏性改变占主导，实质成分被结缔组织取代。
