Malviya S, Burrows F A, Johnston A E, Benson L N
Department of Anaesthesia, Hospital for Sick Children, Toronto, Ontario, Canada.
Can J Anaesth. 1989 May;36(3 Pt 1):320-4. doi: 10.1007/BF03010772.
Anaesthetic and sedation techniques, complications and outcomes were reviewed in 176 children undergoing 184 interventional cardiologic procedures. Techniques included sedation only, and ketamine, inhalational or narcotic anaesthesia. Ketamine infusion was the technique most frequently used. Ketamine was associated with a higher incidence of respiratory complications (P less than 0.05) than the other techniques. The higher incidence of hypercarbia (15.6 per cent), which did not affect outcome, may be attributable to the use of supplemental sedatives. The incidence of upper airway obstruction (7.8 per cent) was similar to that of previous studies. Vascular compromise resulted from the procedure in 33 patients, necessitating surgical correction in 16. Cardiac perforation occurred in four cases, causing one death. Pulmonary valve stenosis was most amenable to balloon dilatation and aortic valve stenosis least amenable. ketamine was the anaesthetic agent preferred by cardiologists for use in the catheterisation suite when general anaesthesia was required. Vigilant monitoring by anaesthetic staff is necessary during the procedure, and avoidance of concomitant narcotics is recommended if a ketamine technique with spontaneous ventilation is used.
对176名接受184例介入性心脏手术的儿童的麻醉和镇静技术、并发症及结果进行了回顾。技术包括单纯镇静、氯胺酮、吸入麻醉或麻醉性麻醉。氯胺酮输注是最常用的技术。与其他技术相比,氯胺酮与更高的呼吸道并发症发生率相关(P小于0.05)。高碳酸血症发生率较高(15.6%),但不影响结果,这可能归因于使用了辅助镇静剂。上呼吸道梗阻发生率(7.8%)与以往研究相似。33例患者因手术出现血管损伤,其中16例需要手术矫正。发生心脏穿孔4例,导致1例死亡。肺动脉瓣狭窄最适合球囊扩张,主动脉瓣狭窄最不适合。当需要全身麻醉时,氯胺酮是心脏病专家在导管室首选的麻醉剂。手术过程中麻醉人员必须进行密切监测,如果采用氯胺酮自主通气技术,建议避免同时使用麻醉性镇痛药。