Chalupa L M, Killackey H P, Snider C J, Lia B
Department of Psychology, University of California, Davis 95616.
Brain Res Dev Brain Res. 1989 Apr 1;46(2):303-8. doi: 10.1016/0165-3806(89)90294-0.
We have studied the distribution of callosal projection neurons in area 17 of a fetal rhesus monkey which received large injections of horseradish peroxidase into the contralateral occipital cortex. In comparison to other cortical areas, area 17 contains few callosal projection neurons. Most of these cells are confined to a region extending tangentially about 2.5 mm from the 17/18 border, although a few neurons were noted as much as 5 mm from the border. Comparing the distribution of callosal projection neurons in the fetal monkey with what has been described in newborn and adult macaques, it is apparent that although some degree of refinement in striate callosal connections may occur during in utero development, the prenatal development of callosal connections in the macaque is inherently adult-like.
我们研究了一只胎儿恒河猴17区胼胝体投射神经元的分布情况，该区域接受了向对侧枕叶皮质大量注射辣根过氧化物酶。与其他皮质区域相比，17区的胼胝体投射神经元较少。这些细胞大多局限于从17/18边界沿切线方向延伸约2.5毫米的区域，不过在距离边界多达5毫米处也发现了一些神经元。将胎儿猴胼胝体投射神经元的分布与新生和成年猕猴中所描述的情况进行比较，很明显，尽管在子宫内发育期间纹状胼胝体连接可能会有一定程度的细化，但猕猴胼胝体连接的产前发育本质上类似成年状态。
