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接受皮质类固醇治疗的犬猫经皮内镜下胃造口术的并发症

Complications of Percutaneous Endoscopic Gastrostomy in Dogs and Cats Receiving Corticosteroid Treatment.

作者信息

Aguiar J, Chang Y M, Garden O A

机构信息

Department of Veterinary Clinical Sciences, Queen Mother Hospital for Animals, Royal Veterinary College, London, United Kingdom.

Research Office, Royal Veterinary College, London, United Kingdom.

出版信息

J Vet Intern Med. 2016 Jul;30(4):1008-13. doi: 10.1111/jvim.13969. Epub 2016 May 23.

Abstract

BACKGROUND

Corticosteroid treatment is commonly required in veterinary patients for treatment of inflammatory, immune-mediated, neurologic, and neoplastic diseases, which also may require assisted enteral nutrition via percutaneous endoscopic gastrostomy (PEG).

OBJECTIVE

To evaluate complications associated with PEG use in dogs and cats receiving corticosteroid treatment.

ANIMALS

Forty-two animals were included in the study: 12 dogs and 2 cats in the steroid group and 26 dogs and 2 cats in the control group.

METHODS

Medical records, between January 2006 and March 2015, were reviewed. Patients were included if the PEG tube was in use for at least 24 hours and if complete medical records were available. Patients were assigned to the control group if they were not treated with corticosteroids during PEG use or to the steroid group if they had received corticosteroids during PEG tube use. Complications were classified as minor, moderate, and major in severity. Maximum severity complication rate was compared between groups.

RESULTS

The general prevalence of complications was found to be similar between groups (P = .306), but in the steroid group, 43% of the cases developed a major severity complication compared with 18% of the control group (P = .054).

CONCLUSION AND CLINICAL IMPORTANCE

Owners of dogs and cats receiving corticosteroids, in which PEG is planned, should be counseled about possible complications beyond those associated with PEG tube usage alone.

摘要

背景

兽医临床上,对于患有炎症性、免疫介导性、神经性和肿瘤性疾病的动物,通常需要使用皮质类固醇进行治疗,而这些疾病可能还需要通过经皮内镜下胃造口术(PEG)进行肠内营养支持。

目的

评估接受皮质类固醇治疗的犬猫使用PEG的并发症。

动物

42只动物纳入研究:类固醇组12只犬和2只猫,对照组26只犬和2只猫。

方法

回顾2006年1月至2015年3月的病历。如果PEG管使用至少24小时且有完整病历,则纳入患者。PEG使用期间未接受皮质类固醇治疗的患者分配至对照组,PEG管使用期间接受过皮质类固醇治疗的患者分配至类固醇组。并发症按严重程度分为轻度、中度和重度。比较两组的最大严重程度并发症发生率。

结果

两组并发症的总体发生率相似(P = 0.306),但类固醇组43%的病例出现严重并发症,而对照组为18%(P = 0.054)。

结论及临床意义

对于计划进行PEG的接受皮质类固醇治疗的犬猫主人,应告知其除单独与PEG管使用相关的并发症外的其他可能并发症。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/edfd/5153948/595e0a2be2af/JVIM-30-1008-g001.jpg

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