Puvanendran K, Cheah J S, Wong P K
Aust N Z J Med. 1977 Oct;7(5):507-10. doi: 10.1111/j.1445-5994.1977.tb03372.x.
Thyrotoxic periodic paralysis (TPP) is produced by a different metabolic disorder than familial periodic paralysis. In the familial disorder, a myopathic cause is well known, but although electromyography can be used to demonstrate the site of the lesion in TPP, such studies are rare in the medical literature and the results are conflicting. In this report, EMG studies were carried out on eight Chinese patients with thyrotoxic periodic paralysis during the attack and the results compared with studies repeated during a remission. Most cases showed a myopathic pattern during an attack of paralysis which disappeared during remission. The myopathic changes noted were a decrease in duration of muscle action potentials, an increase in polyphasic potentials, a satisfactory interference pattern with reduced amplitude and a reduced amplitude of the evoked muscle action potential on nerve stimulation. Peripheral nerve function was normal in the cases studied. It is concluded that the weakness in TPP is myopathic and that the peripheral nerve function during paralysis is normal.
甲状腺毒症性周期性瘫痪（TPP）是由一种与家族性周期性瘫痪不同的代谢紊乱引起的。在家族性疾病中，肌病性病因是众所周知的，但尽管肌电图可用于证明TPP中的病变部位，但此类研究在医学文献中很少见，且结果相互矛盾。在本报告中，对8例甲状腺毒症性周期性瘫痪发作期的中国患者进行了肌电图研究，并将结果与缓解期重复研究的结果进行了比较。大多数病例在瘫痪发作期表现出肌病模式，缓解期消失。观察到的肌病性改变包括肌肉动作电位持续时间缩短、多相电位增加、干扰相满意但振幅降低以及神经刺激诱发的肌肉动作电位振幅降低。在所研究的病例中，周围神经功能正常。结论是，TPP中的肌无力是肌病性的，瘫痪期间周围神经功能正常。
