López Fernando, Devaney Kenneth O, Hanna Ehab Y, Rinaldo Alessandra, Ferlito Alfio
Department of Otolaryngology, Hospital Universitario Central de Asturias, Oviedo, Spain.
University of Oviedo. Instituto Universitario de Oncología del Principado de Asturias, Oviedo, Spain.
Head Neck. 2016 Dec;38(12):1847-1854. doi: 10.1002/hed.24502. Epub 2016 May 24.
The sinonasal cavities are rare locations for metastases. Metastases to these locations are usually solitary and produce similar symptoms to those of a primary sinonasal tumor. Nasal obstruction and epistaxis are the most frequent symptoms. The maxillary sinus is most frequently involved. The most common primary tumor sites to spread to this region originate in the kidney, breast, thyroid, and prostate, although any malignancy could potentially lead to a metastasis to the paranasal sinuses. The patient's prognosis is usually poor because of the fact that the sinonasal metastasis is usually associated with widespread disseminated disease. In the majority of patients, palliative therapy is the only possible treatment option. Nevertheless, whenever possible, surgical excision either alone or combined with radiotherapy may be useful for palliation of symptoms and, rarely, to achieve prolonged survival. This review considers the most interesting cases reported in the literature that presents metastases to the sinonasal cavities. © 2016 Wiley Periodicals, Inc. Head Neck 38: 1847-1854, 2016.
鼻窦是转移瘤的罕见部位。转移至这些部位的肿瘤通常为单发,其产生的症状与原发性鼻窦肿瘤相似。鼻塞和鼻出血是最常见的症状。上颌窦最常受累。尽管任何恶性肿瘤都有可能转移至鼻窦,但转移至该区域的最常见原发肿瘤部位是肾、乳腺、甲状腺和前列腺。由于鼻窦转移瘤通常与广泛播散性疾病相关,患者的预后通常较差。在大多数患者中,姑息治疗是唯一可行的治疗选择。然而,只要有可能,单独手术切除或联合放疗可能有助于缓解症状,很少情况下可实现延长生存期。本文综述了文献中报道的鼻窦转移瘤的最有趣病例。© 2016威利期刊公司。《头颈外科》38: 1847 - 1854, 2016年。