Ludwig K, Scheiffarth O F
Fortschr Ophthalmol. 1989;86(1):38-40.
Sterile inflammatory reactions of varying degree are a rare, but not uncommon complication after intraocular lens implantation. At present we still do not know the cause of these processes, but we consider two chemical substances at least as risk factors for them: the lens content of monomeric methyl methacrylate, which is present in any lens made from polymethyl methacrylate (Perspex), and the lens content of ethylene oxide, an extremely toxic agent, which is absorbed by the lens during sterilization with this gas. Gaschromatographic investigations show that under sterilization of intraocular lenses by Co60-radiation the lens content of monomeric methylmethacrylate can be reduced drastically. Also, any contamination of the lens by ethylene oxide is avoided. Therefore at least two important arguments speak in favour of this alternative sterilization technique.
不同程度的无菌性炎症反应是人工晶状体植入术后一种罕见但并非不常见的并发症。目前我们仍不清楚这些过程的原因,但我们认为至少有两种化学物质是其危险因素:任何由聚甲基丙烯酸甲酯(有机玻璃)制成的晶状体中所含的单体甲基丙烯酸甲酯,以及环氧乙烷,一种剧毒物质,在用这种气体灭菌过程中晶状体会吸收它。气相色谱研究表明,通过钴60辐射对人工晶状体进行灭菌时,单体甲基丙烯酸甲酯在晶状体中的含量可大幅降低。此外,还可避免晶状体受到环氧乙烷的任何污染。因此,至少有两个重要理由支持这种替代灭菌技术。