van Oven M W, Schoots C J, Oosterhuis J W, Keij J F, Dam-Meiring A, Huisjes H J
Department of Pathology, University Hospital of Groningen, The Netherlands.
Hum Pathol. 1989 Mar;20(3):238-42. doi: 10.1016/0046-8177(89)90130-5.
The ploidy of placental tissue from 59 abortions was determined using DNA flow cytometry. The specimens were also screened histologically for features considered to be characteristic of a partial mole. Triploidy was found in six cases; three of these cases presented histologically as partial moles. From the four specimens histologically classified as partial moles, three appeared to be triploid. The most specific histologic features of triploidy were cystic change of the placental villi and trophoblastic hyperplasia with vacuolation of the syncytiotrophoblast; however, these changes were also found in some of the nontriploid abortions. Irregularity of villous contours was less specific.
采用DNA流式细胞术测定了59例流产胎盘组织的倍性。还对标本进行了组织学筛查，以寻找被认为是部分性葡萄胎特征的特征。6例发现三倍体；其中3例在组织学上表现为部分性葡萄胎。在组织学分类为部分性葡萄胎的4个标本中，3个似乎是三倍体。三倍体最具特异性的组织学特征是胎盘绒毛的囊性改变和滋养层细胞增生伴合体滋养层细胞空泡化；然而，这些改变在一些非三倍体流产中也有发现。绒毛轮廓不规则的特异性较低。
