Khan Hamid Sharif, Iftikhar Imran, Khan Qaiser
Department of Cardiology, Armed Forces Institute of Cardiology (AFIC), Rawalpindi.
J Coll Physicians Surg Pak. 2016 May;26(5):353-6.
To determine the validity of electrocardiographic QT interval in predicting left ventricular diastolic dysfunction in patients with suspected heart failure using echocardiogram as the gold standard.
Cross-sectional validation study.
AFIC-NIHD, Rawalpindi, from December 2012 to June 2013.
Patients with suspected heart failure undergoing 12-lead electrocardiogram and echocardiography were inducted. All electrocardiograms were analyzed by a single trained reader unaware of the echocardiographic findings. QTc interval was calculated according to the published guidelines. All patients underwent a complete M mode, 2 dimensional, Doppler, and tissue Doppler echocardiography using aiE33 ultrasound system and diastolic dysfunction was calculated.
Three hundred patients were studied. Descriptive statistics of age was 61.42 years ±10.43. Of all the patients 218 patients (72.7%) were male and 82 patients were female (27.3%). Mean QT interval (msec) was 427.29 ±54.69. One hundred and eighty patients (60.0%) had diastolic dysfunction and 120 patients (40%) had no diastolic dysfunction. The sensitivity of electrocardiographic QTc interval in predicting diastolic dysfunction was 71.11% and specificity was 88.11%.
Prolonged electrocardiographic QTc interval in patients with suspected heart failure is a useful tool in predicting diastolic dysfunction.
以超声心动图作为金标准，确定心电图QT间期在预测疑似心力衰竭患者左心室舒张功能障碍方面的有效性。
横断面验证研究。
2012年12月至2013年6月，拉瓦尔品第的阿菲克 - 尼赫鲁心脏病研究所。
纳入接受12导联心电图和超声心动图检查的疑似心力衰竭患者。所有心电图均由一名对超声心动图检查结果不知情的经过培训的单一读者进行分析。根据已发表的指南计算QTc间期。所有患者均使用aiE33超声系统进行完整的M型、二维、多普勒和组织多普勒超声心动图检查，并计算舒张功能障碍情况。
共研究了300例患者。年龄的描述性统计为61.42岁±10.43岁。所有患者中，218例（72.7%）为男性，82例（27.3%）为女性。平均QT间期（毫秒）为427.29±54.69。180例（60.0%）患者存在舒张功能障碍，120例（40%）患者无舒张功能障碍。心电图QTc间期预测舒张功能障碍的敏感性为71.11%，特异性为88.11%。
疑似心力衰竭患者心电图QTc间期延长是预测舒张功能障碍的有用工具。
