Hawkins Robert B, Frischtak Helena L, Kron Irving L, Ghanta Ravi K
Division of Thoracic and Cardiovascular Surgery, Department of Surgery, University of Virginia Health System, Charlottesville, Virginia.
J Card Surg. 2016 Jul;31(7):446-8. doi: 10.1111/jocs.12764. Epub 2016 May 30.
We present the cases of two patients with bioprosthetic aortic valves who developed an allergy to alpha-gal. Each had premature degeneration of their bioprosthesis and demonstrated rapidly increasing transvalvular gradients after development of their allergy. Each underwent successful replacement with a mechanical aortic valve within 1-2 years of symptom onset. doi: 10.1111/jocs.12764 (J Card Surg 2016;31:446-448).
我们报告了两例生物人工主动脉瓣患者对α-半乳糖过敏的病例。每位患者的生物人工瓣膜均出现过早退化,且在过敏发生后跨瓣膜梯度迅速增加。每位患者在症状出现后的1 - 2年内均成功接受了机械主动脉瓣置换术。doi: 10.1111/jocs.12764(《心脏外科杂志》2016年;31:446 - 448)