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Porcine or bovine valve replacement in 3 patients with IgE antibodies to the mammalian oligosaccharide galactose-alpha-1,3-galactose.

作者信息

Mozzicato Susan M, Tripathi Anubha, Posthumus Jonathon B, Platts-Mills Thomas A E, Commins Scott P

机构信息

Connecticut Asthma and Allergy Center, West Hartford, CT.

Division of Asthma, Allergy and Immunology, Asthma and Allergic Diseases Center, University of Virginia Health System, Charlottesville, VA.

出版信息

J Allergy Clin Immunol Pract. 2014 Sep-Oct;2(5):637-638. doi: 10.1016/j.jaip.2014.04.016. Epub 2014 Jul 25.

Abstract
摘要

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Allergenicity of carbohydrates and their role in anaphylactic events.
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Contaminated heparin associated with adverse clinical events and activation of the contact system.
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The alpha-gal epitope and the anti-Gal antibody in xenotransplantation and in cancer immunotherapy.
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Presence and elimination of the xenoantigen gal (alpha1, 3) gal in tissue-engineered heart valves.
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Alpha-Gal on bioprostheses: xenograft immune response in cardiac surgery.
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