使用7特斯拉磁共振成像进行视神经评估
Optic Nerve Assessment Using 7-Tesla Magnetic Resonance Imaging.
作者信息
Singh Arun D, Platt Sean M, Lystad Lisa, Lowe Mark, Oh Sehong, Jones Stephen E, Alzahrani Yahya, Plesec Thomas
机构信息
Department of Ophthalmic Oncology, Cole Eye Institute, Cleveland Clinic, Cleveland, Ohio, USA.
Imaging Institute, Cleveland Clinic, Cleveland, Ohio, USA.
出版信息
Ocul Oncol Pathol. 2016 Apr;2(3):178-80. doi: 10.1159/000443650. Epub 2016 Jan 27.
PURPOSE
The purpose of this study was to correlate high-resolution magnetic resonance imaging (MRI) and histologic findings in a case of juxtapapillary choroidal melanoma with clinical evidence of optic nerve invasion.
METHODS
With institutional review board approval, an enucleated globe with choroidal melanoma and optic nerve invasion was imaged using a 7-tesla MRI followed by histopathologic evaluation.
RESULTS
Optical coherence tomography, B-scan ultrasonography, and 1.5-tesla MRI of the orbit (1-mm sections) could not detect optic disc invasion. Ex vivo, 7-tesla MRI detected optic nerve invasion, which correlated with histopathologic features.
CONCLUSIONS
Our case demonstrates the potential to document the existence of optic nerve invasion in the presence of an intraocular tumor, a feature that has a major bearing on decision making, particularly for consideration of enucleation.
目的
本研究旨在将1例合并视神经侵犯临床证据的近乳头脉络膜黑色素瘤的高分辨率磁共振成像（MRI）与组织学结果进行关联。
方法
经机构审查委员会批准，对1例患有脉络膜黑色素瘤并伴有视神经侵犯的眼球进行摘除，随后使用7特斯拉MRI进行成像，接着进行组织病理学评估。
结果
光学相干断层扫描、B超扫描以及眼眶的1.5特斯拉MRI（1毫米层厚）均未能检测到视盘侵犯。在离体状态下，7特斯拉MRI检测到了视神经侵犯，这与组织病理学特征相关。
结论
我们的病例表明，在存在眼内肿瘤的情况下，记录视神经侵犯情况具有可能性，这一特征对决策制定具有重大影响，尤其是在考虑眼球摘除时。
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