Henriquez-Rodriguez E, Bosch L, Tor M, Pena R N, Estany J
Departament de Producció Animal, Universitat de Lleida-Agrotecnio Centre, Rovira Roure 191, 25198 Lleida, Spain.
Departament de Producció Animal, Universitat de Lleida-Agrotecnio Centre, Rovira Roure 191, 25198 Lleida, Spain.
Meat Sci. 2016 Nov;121:33-39. doi: 10.1016/j.meatsci.2016.05.012. Epub 2016 May 20.
The effects of the stearoyl-CoA desaturase (SCD; AY487830:g.2228T>C) and leptin receptor (LEPR; NM_001024587:g.1987C>T) polymorphisms on fat content and fatty acid (FA) composition were investigated throughout fattening. Samples of Longissimus thoracis (LT) and subcutaneous fat (SF) from 214 Duroc barrows were collected from 160days to slaughter age (220days) using a longitudinal design. Results indicated that the positive effect of the T allele at the SCD gene on monounsaturated FA and of the T allele at the LEPR gene on saturated FA are maintained throughout the growing-finishing period, both in LT and SF. In LEPR, however, compositional changes, particularly in SF, are a result of increased fatness. There is very limited evidence of genotype by age interaction, and thus it is concluded that the combined selection for the SCD T and LEPR C alleles is a good strategy to increase the MUFA/SFA ratio regardless of the age at slaughter.
研究了硬脂酰辅酶A去饱和酶（SCD；AY487830:g.2228T>C）和瘦素受体（LEPR；NM_001024587:g.1987C>T）基因多态性对育肥全程脂肪含量和脂肪酸（FA）组成的影响。采用纵向设计，采集了214头杜洛克公猪从160日龄到屠宰年龄（220日龄）的胸最长肌（LT）和皮下脂肪（SF）样本。结果表明，SCD基因的T等位基因对单不饱和脂肪酸的正向作用以及LEPR基因的T等位基因对饱和脂肪酸的正向作用在整个生长育肥期的LT和SF中均得以维持。然而，在LEPR基因中，组成变化，尤其是在SF中，是脂肪增加的结果。基因型与年龄交互作用的证据非常有限，因此得出结论，无论屠宰年龄如何，联合选择SCD基因的T等位基因和LEPR基因的C等位基因是提高单不饱和脂肪酸/饱和脂肪酸比例的良好策略。
