Huang Yun-Chen, Peng Steve Shinn-Forng, Hsu Wei-Chung
Department of Otolaryngology, National Taiwan University Hospital and National Taiwan University College of Medicine, Taipei, Taiwan; Department of Otolaryngology, Catholic Cardinal Tien Hospital, Fu-Jen Catholic University, Taipei, Taiwan.
Department of Radiology, National Taiwan University Hospital and National Taiwan University College of Medicine, Taipei, Taiwan.
Int J Pediatr Otorhinolaryngol. 2016 Jun;85:115-9. doi: 10.1016/j.ijporl.2016.03.028. Epub 2016 Mar 28.
This study aims to assess the efficacy of a novel endoscopic management for congenital pyriform sinus fistula (CPSF) using potassium titanyl phosphate (KTP) laser assisted endoscopic tissue fibrin glue biocauterization in children.
From 2010 to 2014, a total of 5 children with recurrent or acute suppurative thyroiditis or neck abscess secondary to CPSF were enrolled retrospectively in this study.
Mean age at the first time of endoscopic biocauterization was 6.2 ± 0.7 (5-7) years. The barium swallow study detected a fistula in four cases. Endoscopy identified an internal opening at the pyriform sinus in all cases with four on the left side and one on the right side. All patients underwent KTP laser assisted endoscopic tissue fibrin glue biocauterization as treatment for CPSF. Only one case required the second endoscopic procedure due to fluctuation of symptoms. Post-endoscopic follow-up duration of these patients was 24.6 ± 11.6 (7-36) months. Neither complications nor recurrences were noted during follow-up in all patients.
For children presenting with repeated acute suppurative thyroiditis or neck infections, clinicians should highly suspect the possibility of CPSF. Endoscopy should be performed not only to confirm the diagnosis but also could be served as an initial treatment modality of biocauterization by KTP laser and tissue fibrin glue, which was demonstrated as a less invasive, safe, and effective method in children.
本研究旨在评估使用磷酸钛氧钾(KTP)激光辅助内镜下组织纤维蛋白胶烧灼术对儿童先天性梨状窝瘘(CPSF)进行新型内镜治疗的疗效。
回顾性纳入2010年至2014年期间5例因CPSF继发复发性或急性化脓性甲状腺炎或颈部脓肿的儿童。
首次内镜烧灼术时的平均年龄为6.2±0.7(5 - 7)岁。吞咽钡剂造影检查在4例中发现瘘管。内镜检查在所有病例中均发现梨状窝有内口,其中左侧4例,右侧1例。所有患者均接受KTP激光辅助内镜下组织纤维蛋白胶烧灼术治疗CPSF。仅1例因症状波动需要进行第二次内镜手术。这些患者内镜术后的随访时间为24.6±11.6(7 - 36)个月。所有患者在随访期间均未出现并发症或复发。
对于出现反复急性化脓性甲状腺炎或颈部感染的儿童,临床医生应高度怀疑CPSF的可能性。内镜检查不仅应进行以确诊,还可作为KTP激光和组织纤维蛋白胶烧灼术的初始治疗方式,这在儿童中被证明是一种侵入性较小、安全且有效的方法。