Philipp S, Kokolakis G, Sabat R
Psoriasis Forschungs- und Behandlungs-Centrum, Klinik für Dermatologie, Venerologie und Allergologie und Institut für Medizinische Immunologie, Charité - Universitätsmedizin Berlin, Charitéplatz 1, 10117, Berlin, Deutschland.
Interdisziplinäre Gruppe Molekulare Immunpathologie, Dermatologie/Med. Immunologie, Charité - Universitätsmedizin Berlin, Berlin, Deutschland.
Hautarzt. 2016 Jun;67(6):464-71. doi: 10.1007/s00105-016-3812-4.
Psoriasis is one of the most common chronic dermatoses. More than 25 % of the affected individuals require effective systemic treatment because of severe symptoms and/or the significantly restricted quality of life. Thanks to intensive research and successful cooperation between academia and the pharmaceutical industry, the options for treating psoriasis have dramatically increased in recent years. Especially targeted therapies give us the opportunity for personalized regimen. This review describes the spectrum of the systemic treatments for psoriasis and psoriatic arthritis and discusses the efficacy, safety, and particular features of the individual substances.
银屑病是最常见的慢性皮肤病之一。超过25%的患者因症状严重和/或生活质量受到显著限制而需要有效的全身治疗。由于学术界和制药行业的深入研究与成功合作，近年来银屑病的治疗选择大幅增加。特别是靶向治疗为我们提供了制定个性化治疗方案的机会。本文综述了银屑病和银屑病关节炎的全身治疗方法，并讨论了各药物的疗效、安全性和特点。
