Collins D
University of Mississippi, Jackson.
J Rheumatol. 1989 Mar;16(3):408-9.
Pancytopenia, rash, and fever developed in a 66-year-old man being treated for metastatic prostate cancer with diethylstilbestrol (DES). Only the withdrawal of DES resulted in the prompt resolution of symptoms, signs, and laboratory manifestations. Both immunologic and endocrinologic mechanisms are implicated and must be considered by physicians using DES for the palliative management of prostate cancer.
一名66岁正在接受己烯雌酚（DES）治疗转移性前列腺癌的男性出现了全血细胞减少、皮疹和发热症状。仅停用DES就使症状、体征和实验室检查结果迅速缓解。免疫和内分泌机制都与之相关，使用DES进行前列腺癌姑息治疗的医生必须予以考虑。
