Adeyemi D
J Trop Pediatr. 1989 Apr;35(2):66-70. doi: 10.1093/tropej/35.2.66.
The experience with 211 cases of neonatal intestinal obstruction in Lagos, Nigeria, is described in an attempt to define the pattern in a developing country. Some of the major differences from the established pattern in the West include absence of meconium ileus and the relatively low prevalence of duodenal atresia which accounted for 8 per cent of bowel obstruction. Jejuno-ileal atresia and Hirschprung's disease constituted 21 and 14 per cent, respectively. Imperforate anus, as in the West, was the commonest, occurring in 38 per cent. Although neonatal intestinal obstruction was seen throughout the year a peak involving all the major types appeared in the second quarter. This may indicate an aetiological relationship with malaria. Delay in presentation, shortage of personnel, and inadequate facilities were the major problems associated with management of neonatal intestinal obstruction. The overall surgical mortality was 35 per cent; respiratory failure, metabolic disturbances, and malabsorption being the major causes of death.
本文描述了在尼日利亚拉各斯对211例新生儿肠梗阻病例的研究经验，旨在明确发展中国家的发病模式。与西方既定模式的一些主要差异包括：无胎粪性肠梗阻，十二指肠闭锁的患病率相对较低，十二指肠闭锁占肠梗阻病例的8%。空肠回肠闭锁和先天性巨结肠分别占21%和14%。与西方情况一样，肛门闭锁最为常见，发生率为38%。虽然全年均可见新生儿肠梗阻，但第二季度出现了涉及所有主要类型的发病高峰。这可能表明与疟疾存在病因学关联。就诊延迟、人员短缺和设施不足是新生儿肠梗阻治疗中存在的主要问题。总体手术死亡率为35%；呼吸衰竭、代谢紊乱和吸收不良是主要死亡原因。
