[伴有浆膜侵犯的胃癌的预后因素——癌浸润至浆膜下层范围的重要性]

[Prognostic factors in gastric cancer with serosal invasion--importance of the extent of cancer infiltration in the subserosal layer].

作者信息

Habu H, Kando F, Saito N, Takeshita K, Sunagawa M, Endo M

机构信息

1st Dept. of Surgery, Tokyo Medical & Dental Univ., School of Med.

出版信息

Gan No Rinsho. 1989 May;35(6):685-9.

PMID:2724547

Abstract

The extent of cancer infiltration in the subserosal layer has been examined in 214 stomachs resected for cancer with a serosal invasion. The extent was 4 cm or less in 109 patients (Group A) and 5 cm or more in 105 patients (Group B). The resection was estimated as being non-curative in 26% of Group A and in 52% of Group B (p less than 0.001). Peritoneal dissemination was the outstanding non-curative factor in the latter. The five-year survival rate was 39% in Group A and 14% in Group B (p less than 0.001). The survival rate after the curative resection was 49% and 26%, respectively (p less than 0.01). In Group B, peritoneal dissemination was the main mode of recurrence after the curative resection.

摘要

对214例因癌侵犯浆膜而切除的胃癌标本，检查了癌组织在浆膜下层的浸润范围。109例患者（A组）浸润范围为4cm或更小，105例患者（B组）浸润范围为5cm或更大。A组26%、B组52%的切除被估计为非根治性切除（p<0.001）。腹膜播散是B组突出的非根治性因素。A组5年生存率为39%，B组为14%（p<0.001）。根治性切除后的生存率分别为49%和26%（p<0.01）。在B组，腹膜播散是根治性切除后复发的主要方式。