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[255例膀胱肿瘤患者的治疗]

[Treatment of 255 patients with bladder tumors].

作者信息

Aso Y, Ushiyama T, Tajima A, Suzuki K, Ohtawara Y, Ohta N, Ohmi Y, Hata M, Masuda H, Kanbayashi T

出版信息

Nihon Hinyokika Gakkai Zasshi. 1989 Jan;80(1):74-81. doi: 10.5980/jpnjurol1989.80.74.

Abstract

During about 10 years from November, 1977 to March, 1987, two hundreds and fifty-five patients with bladder tumors were treated at the Department of Urology, Hamamatsu University School of Medicine and the affiliated hospitals. There were 198 males and 57 females with the highest age incidence in the seventies. Histologically, 242, 11 and 2 tumors were of transitional cell, squamous cell and adenocarcinoma, respectively. Of the 242 transitional cell carcinomas, 7 were Tis; 43 Ta, 111 T1, 33 T2, 19 T3, 5 T4, 14 M+ (with metastatic lesion), and 10 TX. As to grading, 6 was G0; 66 G1, 100 G2, 64 G3, and 6 GX. Staging was correlated with grading. The 5-year survival rates (Kaplan-Meier's method) were 64% in patients with transitional cell carcinoma; 58% in those with squamous cell carcinoma. In patients with transitional cell carcinoma, the 5-year survival rates were 100% for G0, 73% for G1, 73% for G2 and 40% for G3. As to staging, the 5-year survival rates were 67%, 81%, 81%, 35%, 41%, 40% and 12% in patients with stage of Tis, Ta, T1, T2, T3, T4 and M+, respectively. As to the initial treatment, the 5-year survival rates after TUR (137 cases), partial cystectomy (4 cases) and total cystectomy (56 cases) were 81%, 36% and 61%, respectively. The rate of intravesical recurrence after TUR was evaluated with the cumulative non-recurrence rate calculated by Kaplan-Meier's method.(ABSTRACT TRUNCATED AT 250 WORDS)

摘要

在1977年11月至1987年3月约10年的时间里,静冈大学医学院泌尿外科及其附属医院共治疗了255例膀胱肿瘤患者。其中男性198例,女性57例,年龄发病率最高的年龄段为70岁。组织学上,移行细胞癌242例,鳞状细胞癌11例,腺癌2例。在242例移行细胞癌中,Tis期7例;Ta期43例,T1期111例,T2期33例,T3期19例,T4期5例,M+(有转移灶)14例,TX期10例。分级方面,G0期6例;G1期66例,G2期100例,G3期64例,GX期6例。分期与分级相关。移行细胞癌患者的5年生存率(Kaplan-Meier法)为64%;鳞状细胞癌患者为58%。移行细胞癌患者中,G0期5年生存率为100%,G1期为73%,G2期为73%,G3期为40%。分期方面,Tis、Ta、T1、T2、T3、T4和M+期患者的5年生存率分别为67%、81%、81%、35%、41%、40%和12%。初始治疗方面,经尿道膀胱肿瘤切除术(137例)、膀胱部分切除术(4例)和膀胱全切除术(56例)后的5年生存率分别为81%、36%和61%。经尿道膀胱肿瘤切除术后膀胱内复发率采用Kaplan-Meier法计算的累积无复发率进行评估。(摘要截断于250字)

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