局限性转移性非小细胞肺癌的局部治疗：有哪些选择以及是否有益？

Local Therapy for Limited Metastatic Non-Small Cell Lung Cancer: What Are the Options and Is There a Benefit?

作者信息

Iyengar Puneeth, Lau Steven, Donington Jessica S, Suh Robert D

机构信息

From the Department of Radiation Oncology, The University of Texas Southwestern Medical Center, Dallas, TX; NYU School of Medicine, New York, NY; Department of Radiological Sciences, Thoracic Imaging and Intervention, and Diagnostic Radiology Education, David Geffen School of Medicine at UCLA, Los Angeles, CA; Department of Radiation Oncology, Harold C. Simmons Comprehensive Cancer Center, The University of Texas Southwestern Medical Center, Dallas, TX.

出版信息

Am Soc Clin Oncol Educ Book. 2016;35:e460-7. doi: 10.1200/EDBK_158734.

DOI:10.1200/EDBK_158734

PMID:27249754

Abstract

Distant metastasis is common in non-small cell lung cancer (NSCLC) and typically associated with poor prognosis. Aggressive local therapy including surgery and/or radiation for limited metastatic disease from colorectal cancer and sarcoma is associated with survival benefit and has become part of the standard of care. In this article, we review the literature and ongoing studies concerning surgery, radiation, and radiofrequency ablation for oligometastatic NSCLC.

摘要

远处转移在非小细胞肺癌（NSCLC）中很常见，通常与预后不良相关。对于结直肠癌和肉瘤的局限性转移性疾病，积极的局部治疗，包括手术和/或放疗，与生存获益相关，并已成为标准治疗的一部分。在本文中，我们回顾了有关寡转移性NSCLC的手术、放疗和射频消融的文献及正在进行的研究。