Molez J F, Galacteros F, Bosseno M F, Haudrechy D, Kompaore E
ORSTOM, Bobo-Dioulasso, Burkina Faso.
Med Trop (Mars). 1989 Jan-Mar;49(1):33-6.
During a study on malaria in pregnant women in Burkina Faso, the authors gave a particular attention to the hemoglobin of a mother and her new-born child (blood of cord) and they noticed an hemoglobin migrating before the HbA which was identified by isoelectric focusing (IEF). The child is a composite HbK/HbC heterozygote. A survey was carried out to check the transmission of such a K Woolwich hemoglobin within the family of the mother. Out of 40 people, 17 got HbKw. A noticeable anemia was found in HbKw/HbC heterozygote. The authors tried to identified a possible thalassemia. There was little probability for an association of a minor alpha-thalassemia in the absence of Bart's hemoglobin in the blood of the cord (IEF test) and there was no associated beta-thalassemia.
在布基纳法索对孕妇疟疾的一项研究中,作者特别关注了母亲及其新生儿(脐带血)的血红蛋白,他们注意到有一种血红蛋白在通过等电聚焦(IEF)鉴定的HbA之前迁移。该儿童是HbK/HbC复合杂合子。进行了一项调查,以检查这种伍尔维奇K血红蛋白在母亲家族中的传播情况。在40人中,有17人携带HbKw。在HbKw/HbC杂合子中发现了明显的贫血。作者试图确定是否存在可能的地中海贫血。由于脐带血(IEF检测)中没有巴氏血红蛋白,因此合并轻度α地中海贫血的可能性很小,也没有合并β地中海贫血。