Khan Sameer Khalid, Savaridas Terence, Hemers Jennifer S, Maarouf Zouheir, Orgee Jane M, Orr Michael M
Orthopaedic Registrar, Northumbria Healthcare NHS Trust, Ashington, UK.
Upper Limb and Trauma Fellow, Sir Charles Gairdner Hospital, Perth, Australia.
Clin Cases Miner Bone Metab. 2016 Jan-Apr;13(1):38-41. doi: 10.11138/ccmbm/2016.13.1.038. Epub 2016 May 11.
We present 2 cases of elderly females presenting with atraumatic, near-vertical (Pauwells grade 3), intracapsular neck of femur fractures. Following diagnosis of osteoporosis on DEXA scans, they had received alendronic acid for 7 and 10 years respectively. Routine blood tests and serum estimations of calcium, vitamin-D and thyroid-stimulating hormone, done at admission, were within the normal ranges. These patients were managed with a hemiarthroplasty and a dynamic hip screw (DHS) respectively, following discontinuation of bisphosphonates. We present these 2 cases in light of emerging evidence that associates long-term bisphosphonate use with atypical low energy femoral fractures. Only subtrochanteric/diaphyseal fractures have been reported to date. We present a new variant of atypical femoral neck fractures in metaphyseal bone related to prolonged bisphosphonate therapy.
我们报告2例老年女性患者,她们均表现为无创伤性、近乎垂直(Pauwells 3级)的股骨颈囊内骨折。经双能X线吸收法(DEXA)扫描诊断为骨质疏松症后,她们分别接受阿仑膦酸钠治疗7年和10年。入院时进行的常规血液检查以及血清钙、维生素D和促甲状腺激素测定均在正常范围内。在停用双膦酸盐后,这2例患者分别接受了半髋关节置换术和动力髋螺钉(DHS)治疗。鉴于新出现的证据表明长期使用双膦酸盐与非典型低能量股骨骨折有关,我们报告这2例病例。迄今为止,仅报道过转子下/骨干骨折。我们报告了一种与长期双膦酸盐治疗相关的干骺端骨非典型股骨颈骨折的新变体。