Kim Kwang Il, Cha Seung Joo, Lee Chu, Baek Harim, Hwang Seong Don, Cho Mi Young, Jee Bo Young, Park Myoung-Ae
Aquaculture Industry Division, East Sea Fisheries Research Institute, Gangneung, Gangwon-do, 25435, Republic of Korea.
Inland Aquaculture Research Center, Jinhae, Gyeongsangnam-do, 51688, Republic of Korea.
Arch Virol. 2016 Aug;161(8):2305-10. doi: 10.1007/s00705-016-2913-9. Epub 2016 Jun 2.
Infectious hematopoietic necrosis virus (IHNV; n = 18) was identified in the Korean national surveillance program between February 2013 and April 2015, suggesting that IHNV is a major viral pathogen in cultured salmonids. By phylogeny analysis, we found that the JRt-Nagano and JRt-Shizuoka groups could each be further subdivided into three distinct subtypes. The Korean strains were genetically similar to Japanese isolates, suggesting introduction from Japan. Interestingly, the amino acid sequences of the middle glycoprotein gene show that distinct Korean subtypes have circulated, indicating that the settled IHNVs might be evolved stably in cultured salmonid farm environments.
2013年2月至2015年4月期间，韩国国家监测项目中鉴定出传染性造血坏死病毒（IHNV；n = 18），这表明IHNV是养殖鲑科鱼类中的主要病毒病原体。通过系统发育分析，我们发现长野JRt组和静冈JRt组各自可进一步细分为三个不同的亚型。韩国毒株在基因上与日本分离株相似，表明是从日本传入。有趣的是，中间糖蛋白基因的氨基酸序列显示不同的韩国亚型已经传播，这表明定居的IHNVs可能在养殖鲑科鱼类养殖环境中稳定进化。
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