Tamaki M, Nozaki K, Onishi M, Yamamoto K, Ujiie H, Sugahara H
Department of Hematology, Sumitomo Hospital, Osaka, Japan.
Transpl Infect Dis. 2016 Aug;18(4):601-5. doi: 10.1111/tid.12563. Epub 2016 Aug 2.
Central nervous system lomentosporiosis is a rare pathological condition in immunocompromised patients. We describe a fatal case of meningitis caused by Lomentospora prolificans (which was previously named Scedosporium prolificans), after an allogeneic hematopoietic stem cell transplantation (allo-HSCT). To our knowledge, no cases of Lomentospora meningitis following allo-HSCT have been reported previously. Particularly in neutropenic patients, it is important to consider L. prolificans when a fungal infection is suspected and antifungal agents are ineffective.
中枢神经系统多育弯孢霉病是免疫功能低下患者中一种罕见的病理状况。我们描述了1例异基因造血干细胞移植（allo-HSCT）后由多育弯孢霉（曾被命名为多育拟青霉）引起的致命性脑膜炎病例。据我们所知，此前尚无allo-HSCT后发生多育弯孢霉脑膜炎的病例报道。特别是在中性粒细胞减少的患者中，当怀疑有真菌感染且抗真菌药物无效时，考虑多育弯孢霉感染很重要。
