Chekani Farid, Bali Vishal, Aparasu Rajender R
Department of Pharmaceutical Health Outcomes and Policy, College of Pharmacy, University of Houston, Texas Medical Center, Houston, TX, USA.
Senior Health Outcomes Researcher, Health Advocate, Westlake Village, CA, USA.
J Parkinsons Dis. 2016 Jun 2;6(3):617-24. doi: 10.3233/JPD-160822.
Parkinson's disease (PD) is a debilitating neurological disorder that has a significant impact on activities of daily living (ADL). Limited data exists regarding the functional status of nursing home residents with PD.
The study examined the nature, extent, and predictors of limitation of ADL in patients with PD residing in nursing homes.
This study used cross-sectional design involving data from the National Nursing Home Survey (NNHS). The dependent variable was the total number of ADL for which the patient needed assistance. Assistance for ADL comprised of five items of transferring, dressing, eating, toileting and bathing. Multivariable linear regression was used to examine the individual, biological and environmental factors associated with assistance needed for ADL.
The nationally representative study sample was of 98,093 nursing home residents with PD for an overall prevalence of 6.57%. The mean age of the study sample was 81.03±0.34 years. Mood symptoms (45%), behavioral symptoms (24%)and dementia (8%) were common among PD patients. Assistance needed for each ADL ranged from 68.24% for eating to 99.25% for bathing. Older age, being married, living in metropolitan statistical area (MSA), living in other place prior to admission, and presence of mood symptoms were positively related to assistance for ADL. Presence of behavioral symptoms and use of levodopa combination therapy were negatively related to assistance for ADL.
Majority of the nursing home residents with PD had disability in all the five items of ADL. Various individual, environmental and biological factors were associated with ADL in nursing home residents with PD.
帕金森病(PD)是一种使人衰弱的神经疾病,对日常生活活动(ADL)有重大影响。关于患有帕金森病的疗养院居民的功能状况的数据有限。
本研究调查了居住在疗养院的帕金森病患者日常生活活动受限的性质、程度和预测因素。
本研究采用横断面设计,涉及来自国家疗养院调查(NNHS)的数据。因变量是患者需要协助的日常生活活动总数。日常生活活动协助包括转移、穿衣、进食、如厕和洗澡五个项目。采用多变量线性回归来研究与日常生活活动所需协助相关的个人、生物和环境因素。
具有全国代表性的研究样本为98093名患有帕金森病的疗养院居民,总体患病率为6.57%。研究样本的平均年龄为81.03±0.34岁。帕金森病患者中常见情绪症状(45%)、行为症状(24%)和痴呆(8%)。每项日常生活活动所需协助的比例从进食的68.24%到洗澡的99.25%不等。年龄较大、已婚、居住在大都市统计区(MSA)、入院前居住在其他地方以及存在情绪症状与日常生活活动协助呈正相关。存在行为症状和使用左旋多巴联合疗法与日常生活活动协助呈负相关。
大多数患有帕金森病的疗养院居民在所有五项日常生活活动中都存在残疾。各种个人、环境和生物因素与患有帕金森病的疗养院居民的日常生活活动相关。