Grandini S A
Oral Surg Oral Med Oral Pathol. 1978 Feb;45(2):190-9. doi: 10.1016/0030-4220(78)90085-3.
A histologic study of the effects of diabetes on wound healing of dental sockets was undertaken in rats. The diabetic sate was achieved by performing partial pancreatectomies. The subjects were perfused with 25 percent glutaraldehyde (fixation) and the healing sockets were studied at 3-day intervals during a period of 22 days. The delayed healing observed in this study, when the diabetic condition was due to partial pancreatectomy, was not influenced by the technique used, but was the result of the metabolic modifications of the induced disease.
对大鼠进行了一项关于糖尿病对牙槽窝伤口愈合影响的组织学研究。通过实施部分胰腺切除术来诱导糖尿病状态。将实验对象用25%的戊二醛进行灌注(固定),并在22天的时间内每隔3天对愈合中的牙槽窝进行研究。在本研究中观察到,当糖尿病状态是由部分胰腺切除术导致时,延迟愈合不受所用技术的影响,而是所诱发疾病代谢改变的结果。