Chen Hui, Aarab Ghizlane, Parsa Azin, de Lange Jan, van der Stelt Paul F, Lobbezoo Frank
Department of Oral and Maxillofacial Radiology and Department of Oral Kinesiology, Academic Centre for Dentistry Amsterdam (ACTA), University of Amsterdam and VU University Amsterdam, The Netherlands.
Assistant Professor, Department of Oral Kinesiology, Academic Centre for Dentistry Amsterdam (ACTA), University of Amsterdam and VU University Amsterdam, MOVE Research Institute Amsterdam, Amsterdam, The Netherlands.
Oral Surg Oral Med Oral Pathol Oral Radiol. 2016 Jul;122(1):104-10. doi: 10.1016/j.oooo.2016.04.005. Epub 2016 Apr 23.
The aim of this study was (1) to assess intra- and interobserver reliability of the localization of anatomic landmarks of the upper airway on cone beam computed tomography (CBCT) images; and (2) to assess intra- and interobserver reliability of the three-dimensional measurements of the upper airway based on these landmarks.
Fifteen NewTom 5G (QR systems, Verona, Italy) CBCT data sets were randomly selected from the archives of the Department of Oral Radiology, Academic Centre for Dentistry (ACTA) at University of Amsterdam and VU University, Amsterdam, The Netherlands. Three observers localized six anatomic landmarks that are relevant for upper airway analysis twice, with a 10-day interval, using 3Diagnosys software (v5.3.1, 3diemme, Cantu, Italy). Subsequently, the observers performed upper airway volume measurement based on those landmarks twice as well, again with a 10-day interval, using Amira software (v4.1, Visage Imaging Inc., Carlsbad, CA). The upper airway measurements also included the minimum cross-sectional area (CSAmin), location of the CSAmin, and anteroposterior and lateral dimensions of the CSAmin.
Both intraobserver reliability and interobserver reliability were excellent for the localization of the anatomic landmarks of the upper airway (intraclass correlation coefficients = 0.97-1.00) as well as for the three-dimensional upper airway measurements (intraclass correlation coefficients = 0.78-1.00).
The methodology of landmark localization and upper airway measurements, as used in this study, showed an excellent reliability and can thus be recommended for upper airway analysis on CBCT images.
本研究的目的是（1）评估锥形束计算机断层扫描（CBCT）图像上气道解剖标志定位的观察者内和观察者间可靠性；（2）评估基于这些标志的上气道三维测量的观察者内和观察者间可靠性。
从荷兰阿姆斯特丹大学牙科学术中心（ACTA）口腔放射科档案中随机选取15个NewTom 5G（QR系统，意大利维罗纳）CBCT数据集。三名观察者使用3Diagnosys软件（v5.3.1，3diemme，意大利坎图），在间隔10天的情况下，对与上气道分析相关的六个解剖标志进行两次定位。随后，观察者再次使用Amira软件（v4.1，Visage Imaging Inc.，美国加利福尼亚州卡尔斯巴德），基于这些标志对气道容积进行两次测量，同样间隔10天。上气道测量还包括最小横截面积（CSAmin）、CSAmin的位置以及CSAmin的前后径和左右径。
上气道解剖标志定位的观察者内可靠性和观察者间可靠性均极佳（组内相关系数 = 0.97 - 1.00），上气道三维测量的观察者内可靠性和观察者间可靠性也极佳（组内相关系数 = 0.78 - 1.00）。
本研究中使用的标志定位和上气道测量方法显示出极佳的可靠性，因此可推荐用于CBCT图像上的上气道分析。
