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变应性鼻炎青少年及成人患者 MACVIA 临床决策算法。

MACVIA clinical decision algorithm in adolescents and adults with allergic rhinitis.

机构信息

University Hospital, Montpellier, France; MACVIA-LR, Contre les MAladies Chroniques pour un VIeillissement Actif en Languedoc-Roussillon, European Innovation Partnership on Active and Healthy Ageing Reference Site, Montpellier, France; INSERM, VIMA: Ageing and Chronic Diseases, Epidemiological and Public Health approaches, Paris, and Université Versailles St-Quentin-en-Yvelines, St-Quentin-en-Yvelines, France.

Departments of Clinical Epidemiology and Biostatistics and Medicine, McMaster University, Hamilton, Ontario, Canada.

出版信息

J Allergy Clin Immunol. 2016 Aug;138(2):367-374.e2. doi: 10.1016/j.jaci.2016.03.025. Epub 2016 Apr 23.

Abstract

The selection of pharmacotherapy for patients with allergic rhinitis (AR) depends on several factors, including age, prominent symptoms, symptom severity, control of AR, patient preferences, and cost. Allergen exposure and the resulting symptoms vary, and treatment adjustment is required. Clinical decision support systems (CDSSs) might be beneficial for the assessment of disease control. CDSSs should be based on the best evidence and algorithms to aid patients and health care professionals to jointly determine treatment and its step-up or step-down strategy depending on AR control. Contre les MAladies Chroniques pour un VIeillissement Actif en Languedoc-Roussillon (MACVIA-LR [fighting chronic diseases for active and healthy ageing]), one of the reference sites of the European Innovation Partnership on Active and Healthy Ageing, has initiated an allergy sentinel network (the MACVIA-ARIA Sentinel Network). A CDSS is currently being developed to optimize AR control. An algorithm developed by consensus is presented in this article. This algorithm should be confirmed by appropriate trials.

摘要

过敏性鼻炎(AR)患者的药物治疗选择取决于多个因素,包括年龄、主要症状、症状严重程度、AR 控制情况、患者偏好和成本。过敏原暴露和由此产生的症状各不相同,需要进行治疗调整。临床决策支持系统(CDSS)可能有助于评估疾病控制情况。CDSS 应基于最佳证据和算法,以帮助患者和医疗保健专业人员共同确定治疗方案以及根据 AR 控制情况逐步升级或降级的策略。朗格多克-鲁西永大区积极老龄化慢性病防治伙伴关系(MACVIA-LR)是积极和健康老龄化欧洲创新伙伴关系的参考点之一,已启动了过敏症监测网络(MACVIA-ARIA 监测网络)。目前正在开发 CDSS 以优化 AR 控制。本文介绍了一种通过共识达成的算法。该算法应通过适当的试验加以确认。

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