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经口激光显微手术治疗部分喉重建术后喉狭窄

Transoral laser microsurgery for managing laryngeal stenosis after reconstructive partial laryngectomies.

作者信息

Lucioni Marco, Bertolin Andy, Lionello Marco, Giacomelli Luciano, Ghirardo Guido, Rizzotto Giuseppe, Marioni Gino

机构信息

Otolaryngology Unit, Vittorio Veneto Hospital, Vittorio Veneto, Italy.

Department of Medicine DIMED, University of Padova, Padova, Italy.

出版信息

Laryngoscope. 2017 Feb;127(2):359-365. doi: 10.1002/lary.26056. Epub 2016 Jun 3.

Abstract

OBJECTIVES/HYPOTHESIS: To retrospectively analyze our experience of transoral laser microsurgery (TLM) for treating postoperative laryngeal obstruction (POLO) after supracricoid and supratracheal laryngectomy (open partial horizontal laryngectomy [OPHL]) types 2 and 3, and to investigate potential relationships between patients' clinical features and their functional outcomes.

STUDY DESIGN

A retrospective cohort study.

METHODS

The prognostic influence of clinical and surgical parameters on functional outcomes was investigated in a univariate statistical setting in terms of decannulation rate (DR), time to tracheostomy closure (TTC), and number of laser procedures required (NLP).

RESULTS

OPHL type 2 was associated with a better functional outcome than OPHL type 3 in terms of DR, TTC, and NLP (P = .03, P = .02, and P = .02, respectively). Annular and semicircumferential stenoses developed more frequently after OPHL type 3, and were particularly difficult to manage with TLM. Fixation of the residual arytenoid was a negative prognostic factor in terms of functional outcome in terms of DR, TTC, and NLP (P = .0002, P = .08, and P = .08, respectively).

CONCLUSIONS

There is no standardized laser treatment for POLO; it must be tailored to individual patients. Identifying prognostic factors influencing functional outcome could help surgeons to earmark patients less likely to benefit from TLM for the treatment of POLO, and enable an adequate preoperative counseling, given the high probability of repeat postoperative TLM procedures.

LEVEL OF EVIDENCE

4 Laryngoscope, 2016 127:359-365, 2017.

摘要

目的/假设:回顾性分析我们采用经口激光显微手术(TLM)治疗环状软骨上和气管上喉切除术(开放式部分水平喉切除术[OPHL])2型和3型术后喉梗阻(POLO)的经验,并研究患者临床特征与其功能结局之间的潜在关系。

研究设计

一项回顾性队列研究。

方法

在单变量统计环境中,根据拔管率(DR)、气管造口闭合时间(TTC)和所需激光手术次数(NLP),研究临床和手术参数对功能结局的预后影响。

结果

就DR、TTC和NLP而言,2型OPHL的功能结局优于3型OPHL(分别为P = 0.03、P = 0.02和P = 0.02)。3型OPHL后环状和半环状狭窄更频繁出现,且采用TLM治疗特别困难。就DR、TTC和NLP的功能结局而言,残余杓状软骨固定是一个负面预后因素(分别为P = 0.0002、P = 0.08和P = 0.08)。

结论

对于POLO没有标准化的激光治疗方法;必须针对个体患者进行调整。识别影响功能结局的预后因素有助于外科医生确定哪些患者不太可能从TLM治疗POLO中获益,并鉴于术后重复进行TLM手术的可能性很高,能够进行充分的术前咨询。

证据水平

4《喉镜》,2016年127卷:359 - 365页,2017年。

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