Perry C R
Department of Surgery, Washington University School of Medicine, St. Louis, Missouri.
Orthop Rev. 1989 May;18(5):626-30, 635-7, 643-5.
We present our technique and results in using an implantable drug pump to deliver antibiotics locally in the treatment of two specific orthopaedic infections: chronic recalcitrant osteomyelitis and acutely infected total joints. This method of antibiotic delivery in conjunction with appropriate surgical management results in prolonged suppression of infection in 71% of patients with chronic recalcitrant osteomyelitis. In acutely infected arthroplasties we were able to salvage the prosthesis and suppress the infection in 18 of 20 cases.
