Zanella Marie-Céline, Kressmann Benjamin, Wuarin Lydia, Coulin Benoit, Maître Sophie, Suva Domizio, Lipsky Benjamin A, Uçkay Ilker
Rev Med Suisse. 2016 Apr 13;12(514):732-7.
In diabetic patients, foot ulcer is a common problem which prevalence during life is about 25%. Infection occurs as a complication in almost 50% of cases, is associated with significant morbidity and a reduced quality of life and is sometimes the trigger leading to amputation. Ulcers and infections occur among patients with predisposing factors such as peripheral neuropathy and arterial insufficiency, and require a multi-disciplinary care system. The knowledge of the microbiology of diabetic foot infection is necessary for a wise use of empirical and targeted antibiotic therapy. This article will focus on the definition and diagnosis of diabetic foot infection, on the main aspects of its microbiology and antibiotic treatment.
在糖尿病患者中,足部溃疡是一个常见问题,其一生中的患病率约为25%。几乎50%的病例会发生感染并发症,这与严重的发病率和生活质量下降相关,有时还是导致截肢的诱因。溃疡和感染发生在有周围神经病变和动脉供血不足等易感因素的患者中,需要多学科护理系统。了解糖尿病足感染的微生物学知识对于合理使用经验性和靶向性抗生素治疗至关重要。本文将重点关注糖尿病足感染的定义和诊断、其微生物学及抗生素治疗的主要方面。