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[动脉高血压职业风险的识别。1:消除心血管风险因素的修正影响]

[IDENTIFICATION OF OCCUPATIONAL RISK FOR ARTERIAL HYPERTENSION. 1: ELIMINATION OF THE MODIFYNG INFLUENCE OF FACTORS OF CARDIOVASCULAR RISK].

作者信息

Maksimov S A, Mikhailuts A P, Artamonova G V

出版信息

Gig Sanit. 2016;95(3):262-6.

Abstract

On results of research in 13 occupational groups (3842 workers, men) there were performed an analysis of a contribution of non-occupational factors of cardiovascular risk (FCVRs) and the elimination of their modifying influence on risks for the development of the arterial hypertension (AH). In the capacity of non-occupational FCVRs there were considered 16 predictors of AH. There were calculated the relative risk of AH and 95% the confidential interval (CI) in occupational groups on benchmark data of the prevalence rate of AH and after the elimination of the modifying influence of FCVRs. Reference group was the general sample, that is, all the occupations. Modifying influence of FCVR was eliminated by means of direct standardization. With the aid of trees of classifcation from the number of FCVRs in occupational groups the presence of obesity and age of the worker (respectively, 100 and 78 conditional points) was shown to have the maximum impact on the development of AH. Elimination of the influence of data of FCVRs led to the change of benchmark values of occupational risks of AH in the average for 10%, in four occupations level of the statistical importance of risks of AH changed. In top-managers, and also in operating personnel and technical workers the risk for AH from the high decreased to not significant, respectively to 1,00 at 95%, CI: 0.74-1.36 and 1.20 at 95%, CI: 0.97-1.49. On the contrary, the risk for AH increased from low to statistically not significant in underground equipment operators (0.85 at 95%, CI: 0.71-1.01) and labourers (0.89 at 95%, CI: 0.69-1.14).

摘要

对13个职业群体(3842名男性工人)的研究结果进行了分析,以探讨心血管疾病非职业风险因素(FCVRs)的作用,并消除其对动脉高血压(AH)发病风险的修饰影响。作为非职业FCVRs,研究考虑了16个AH预测因素。根据AH患病率的基准数据以及消除FCVRs的修饰影响后,计算了职业群体中AH的相对风险和95%置信区间(CI)。参照组为总体样本,即所有职业。通过直接标准化消除了FCVR的修饰影响。借助职业群体中FCVR数量的分类树,结果显示肥胖和工人年龄(分别为100和78个条件点)对AH的发生影响最大。消除FCVR数据的影响导致AH职业风险的基准值平均变化了10%,在四个职业中,AH风险的统计重要性水平发生了变化。在高层管理人员以及操作人员和技术工人中,AH的高风险分别降至无统计学意义,95%CI时分别为1.00(CI:0.74 - 1.36)和1.20(CI:0.97 - 1.49)。相反,在地下设备操作员(95%CI时为0.85,CI:0.71 - 1.01)和体力劳动者(95%CI时为0.89,CI:0.69 - 1.14)中,AH的风险从低增加到无统计学意义。

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