Guibert N, Milia J D, Mazieres J
Service de pneumologie, hôpital Larrey, CHU de Toulouse, université Paul-Sabatier, 31000 Toulouse, France.
Service de pneumologie, hôpital Larrey, CHU de Toulouse, université Paul-Sabatier, 31000 Toulouse, France.
Rev Mal Respir. 2016 Oct;33(8):675-681. doi: 10.1016/j.rmr.2016.01.007. Epub 2016 Jun 3.
Lung cancers are common malignancies, which have a very poor prognosis. These are the leading cause of cancer deaths in France and worldwide. Behind this unfavourable prognosis hides many disparities according to age, sex, social level and exposure to risk factors. The detection of the genetic abnormalities, which drive carcinogenesis has totally changed the therapeutic approach. Tumours are now classified according to their molecular profile which is itself associated with new demographic data. We here review the most recent data on this topic.
肺癌是常见的恶性肿瘤，预后很差。它们是法国乃至全球癌症死亡的主要原因。在这种不良预后背后，隐藏着许多因年龄、性别、社会阶层和接触风险因素而产生的差异。驱动致癌作用的基因异常的检测彻底改变了治疗方法。肿瘤现在根据其分子特征进行分类，而分子特征本身又与新的人口统计学数据相关。我们在此回顾关于这一主题的最新数据。
